These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA
protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.
«We wanted to develop a newborn screen for NPC because we know that the earlier we intervene with investigational
treatments in animal models of the disease, the longer the animals live,» said Ory, the Alan A. and Edith L. Wolff Distinguished Professor of Medicine.
Once this work is completed, a second stage is committed, in which researchers of I - Stem, in collaboration with
specialists in animal models of diseases targeted by the therapeutic explore the effects of experimental transplantation of cells obtained laboratory.
Some evidence of the involvement of retinal tissue hypoxia has come from in vivo
measurements in animal models of disease, though the onset of hypoxia and the severity of the insult have been difficult to identify.
One potential reason for this discrepancy is that the laboratory tests
used in animal models of the disease do not resemble the clinical assessments given to patients, and thus are not predictive of human memory performance.
Using a drug that blocks the production of a certain type of immune cell linked to inflammation and autoimmunity, the researchers successfully protected against the onset of
MS in an animal model of the disease.
In view of the critical importance of these interactions in normal cardiovascular functin and disease, there has been a great need for an approach to combine in vivo measurement and imaging of paramagnetic molecules with imaging of tissue and organ biochemical and functional
parameters in animal models of disease.
SAN FRANCISCO, CA — Scientists at the Gladstone Institutes have discovered that an FDA - approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer's - related
impairments in an animal model of the disease.
In animal models of disease, iPSCs have been used to treat sickle cell anemia, Parkinson's disease, diabetes, spinal cord injuries, and heart failure.
He also showed that DBSI could be used to examine the development of white matter inflammation in patients with neurodegenerative diseases and
in animal models of these diseases.