This cholesterol lowering effect is highly significant since each 1 %
drop in serum cholesterol translates to a 2 % decrease in the risk of developing heart disease.
Weight gain was recorded in both groups, but the group that consumed the muffins with polyunsaturated fatty acids experienced
decreases in serum cholesterol levels.
We used linear regression to examine whether assignment to diet group or
changes in serum cholesterol concentration were associated with coronary or aortic atherosclerosis.
Diets that cause an essential fatty acid deficiency always produce an increase
in serum cholesterol levels as well as an increase in the atherosclerotic indices.
In a similar heart study, rodents dosed with phytic acid registered a drop
in serum cholesterol of 32 percent and a decrease in triglycerides of 64 percent.
The control diet, which increased dietary linoleic acid by 38 % but did not alter saturated fat, produced a modest but significant reduction
in serum cholesterol compared with baseline (− 5 mg / dL (SD 30 mg / dL); − 1.0 % (SD 14.5 %); P < 0.001)(fig 3 ⇑ and table 2 ⇑).
More specifically, among both groups combined in one review, they found a 30 mg / dL decrease
in serum cholesterol created a 22 percent higher risk of death from any cause.
After adjustment for intake of meat, beer, potatoes, root crops, and vegetables the associations were weakened, but significant inverse associations remained between 15:0
in serum cholesterol esters and body weight and BMI (data not shown).
A 30mg / dL
decrease in serum cholesterol was associated with a 22 percent increase in the risk of death from any cause, even after adjusting for baseline cholesterol, age, sex, adherence to the diet, body mass and blood pressure.
For simplicity, we have shown hazard ratios for each 30 mg / dL (0.78 mmol / L) decrease
in serum cholesterol.
Higher adherence to the control diet was also associated with greater reduction
in serum cholesterol (P = 0.004).
The relations between the proportions of 15:0
in serum cholesterol esters and phospholipids and the studied clinical characteristics are shown in Table 9.
these patients experienced a 22 % higher risk of death for each 30 mg / dfL reduction in serum cholesterol
According to this re-analysis, these patients experienced a 22 % higher risk of death for each 30 mg / dfL reduction
in serum cholesterol (Ramsden et al., 2016).