Sentences with phrase «in zebrafish»

In addition to seeing green lymphatic cells in the zebrafish embryos, the researchers noticed that green cells also covered the surface of the tiny fish's brains.

This week, Fior, who is at the Champalimaud Centre for the Unknown in Lisbon, and her colleagues reported growing implanted human tumor cells in zebrafish larvae.

Dr. Zohar Ben - Moshe from the Yoav Gothilf Lab identified 14 light - entrained molecular clock genes in the zebrafish system using messenger RNA sequencing and microarray analysis.

Drug screening in a zebrafish model of SCN1A mutation has identified lead compounds for development of novel therapies.

«BPA and BPS (substitute for BPA) affect embryonic brain development in zebrafish: Low levels of chemicals linked to hyperactivity.»

«In order to be able to research more closely what effect PSENEN has, we, in collaboration with Prof. Odermatt, deactivated the gene in some zebrafish larvae and then compared these with normal larvae under the microscope,» explains Damian Ralser.

We will use the power of modeling tumors in zebrafish in combination with patient derived cell lines and tumors and murine xenograft models to define tumor heterogeneity.

So she teamed up with cell biologist Serge Mostowy of Imperial College London for a study in zebrafish.

Initial work at the firm will involve research into a particular drug that, according to tests, can double the rate at which complex tissues in zebrafish regrow after amputation.

Matthew Oberholtzer, Cape Elizabeth, Maine; University of Maine; mentor: Vicki P. Losick, Ph.D., assistant professor, MDI Biological Laboratory; research topic: A study of cilia importance in zebrafish heart regeneration

Taking the example of cocaine, researchers at Eawag, together with colleagues at Zurich University, have now shown that the uptake and distribution patterns and the effects of the drug in zebrafish differ in many ways from those in mammals.

In this figure we show that both mouse and zebrafish control regions for the alpha A-crystallin gene work in zebrafish embryos.

Close - up of muscle fibres in a zebrafish with the protein, actin, labelled with green fluorescent protein (GFP) Image credit: Elisabeth Busch, Wellcome Trust Sanger Institute

We further validated the pathogenic nature of this mutation by knocking down its expression in zebrafish embryos, which resulted in a developmental defect.

Scientists established the importance of Stac3 for muscle function in zebrafish by studying the small fish physiologically and genetically.

Knockdown of dynamin - binding protein or Tuba results in abnormal kidney development and other aberrant phenotypes in zebrafish models (middle and right panels) compared with controls (left panel).

The Yoav Gothilf Lab (Tel Aviv University, Israel) has done some very in - depth research on the mechanism behind the light entrainment of the circadian system in zebrafish.

Then the researchers genetically knocked out the α - synuclein protein in the zebrafish and exposed them to ziram again.

Stainier and colleagues, meanwhile, recently reported other findings in the zebrafish embryo that reveal basic mechanisms of development and could lead to an understanding of some birth defects.

From these tracks detailed analysis of freezing behavior and erratic movements was performed to assess fear behavior in the zebrafish.

In addition, we model genetic cardiac diseases in zebrafish.

Groups of red and green labelled embryonic cells in a zebrafish during their first migration in gastrulation.

These studies demonstrate that inflammatory intestinal pathologies, such as Hirschsprung - associated enterocolitis or inflammatory bowel disease, can be explained as an overgrowth of certain pro-inflammatory groups of bacteria or a loss of anti-inflammatory bacteria, said Judith Eisen, a professor of biology and an expert on gut neurons in zebrafish.

In four out of five cases, the response of the tumors in the zebrafish avatars correctly predicted whether the patients» tumors would rebound within 3 months to 6 months after surgery, the team reports in the Proceedings of the National Academy of Sciences.

While studying the basic function of the IKK complex in zebrafish and mice, researchers at the Salk Institute for Biological Studies discovered that one subunit reigns in the activity of the other instead of boosting it, as was widely believed before.

Building on the evidence that microglia were in play during injury, the researchers conducted tests in zebrafish with the specialized enzyme incorporated into both rod cells and microglial cells, removing both cell types to ask what role microglia play during regeneration.

10:35 - 10:55 Johan Lindberg, Swetox and Jonathan Benskin, Stockholm University, Dept. Applied Environmental Science Molecular phenotyping in zebrafish using metabolomics

«The fact that the key elements of stress and stress response are conserved in zebrafish is exciting because of the many experimental advantages of that model organism,» says chemical geneticist Randall Peterson of the Massachusetts General Hospital, Harvard Medical School, Charlestown.

Soon after, an alarm sounded at the fish facility down the hall, and Jesus Torres - Vasquez, who studies blood - vessel formation in zebrafish, came up to check.

Scientists have released video showing immune cell migration in the Zebrafish inner ear.

Regeneration of cryoinjury induced necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte proliferation.

However, the missing cells make Pro-melanin concentrating hormone (Pmch), a brain signal that was not perturbed in zebrafish.

For the study, researchers created a model of the human degenerative retinal disease, retinitis pigmentosa, in zebrafish by incorporating a gene for a specialized enzyme into the rod cells of the fish retina.

A new study at the University of Oregon, led by postdoctoral fellow Annah Rolig, took aim at that question with experiments in zebrafish to dissect whether changes in the abundance of certain gut bacteria can cause intestinal inflammation.

His group studies the cellular and genetic control of gastrulation movements in zebrafish, one of the model organisms studied at the institute besides Drosophila, the C. elegans worm, frogs, mice, and newts.

The working group of Didier Stainier from the Max Planck Institute for Heart and Lung Research has now, together with scientists from the University of San Diego, identified in zebrafish a novel mechanism, at which muscle cells from the atrium actively migrate into damaged parts of the heart muscle in the ventricle, thus forming new ventricular tissue.

Surprisingly, the researchers found a similar bimodal 3 - dimensional chromatin architecture in the Hoxd gene region in zebrafish embryos.

In Vivo Imaging of Cancer in Zebrafish.

By linking human genes to their closest comparators in the zebrafish genome (orthologs) we are able to investigate what happens when a gene is lost or isn't working the way it should.

Behavioral testing Studies of behaviour in zebrafish has emerged as a relevant read out for studying the effect of pollutants and drug waste products in water.

Rieger conducted her research in zebrafish exposed to paclitaxel, a chemotherapeutic agent used for ovarian, breast, lung, pancreatic and other cancers.