Sentences with phrase «kb region»

We constructed a targeting vector by deleting a ~ 2.6 kb region containing exons 1 and 2 and ~ 1 kb of the sequence upstream of exon1 and used the vector to generate the knockout mouse.

In this study, researchers found that the Bt locus was delimited to a 442 - kb region on chromosome 5 that harbors 67 predicted genes.

De novo assembly of > 1 kb regions in the absence of a reference genome produced contiguous sequences (contigs) that aligned with highest similarity to XMRV genomes and not to related MLVs (data not shown).

Indeed, we found six 500 Kb regions significantly enriched for decreased methylation in the CPA group compared to the control group (Table 3).

Shaded in blue is a 500 Kb region containing protocadherins family A and B whose promoters are consistently less methylated in CPA than in controls (scale log2 fold differences: − 0.2 to 0.2).

(b) Human neocentromere 10q25.3 contains an approximately 330 kb CenH3 - binding domain contained in an approximately 700 kb region that can be precipitated with CREST # 6 antibodies and is flanked by late - replicating regions.

As with other positional cloning studies, our data do not rule out alternative scenarios that could link causative sequence changes in the 13.5 kb region to wing size, such as (undetected) effects on prospero or long - distance regulation of a different gene.

To measure the strength of this clustering, we partitioned the genome into 500 Kb regions and asked whether each region contained a surprisingly high number of differentially methylated probes.