Sentences with phrase «key signal»

In particular, his laboratory focuses on the regulation of key signaling networks that regulate cancer cell growth and survival.

A fourth study finds that a generalized seizure leads to diminished short and long - term memory by interfering with key signaling pathways in the brain.

While trending information can be insightful, reliance on just analytics will result in the missing of key signals related to context.

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Other key signals for the Anthropocene considered by the group include the introduction of plastic and other novel materials, fossil fuel combustion and carbon dioxide concentration, and extinctions and invasive species.

Multiple compounds with the Super DMZ 5.0 formula have been clinically demonstrated to activate / inhibit key signaling cascades involved in the regulation of blood glucose, glycogen synthesis, fatty acid synthesis, transcriptional regulation, and cytokine - mediated inflammation.

Because insulin and leptin act as key signals in regulating how much food you eat, as well as your body weight, dietary fructose can also contribute to increased food intake and weight gain.

Sep. 4, 2014 — Vanderbilt University researchers have received multi-year grants from two private foundations to investigate key signaling proteins that could lead to novel treatments for autism spectrum disorder (ASD) and dystonia, a movement disorder.

Other key signals: Approaching with tail up: This is a cat's way of greeting you.

Florentine Rutaganira wants to use chemical tools to decipher the roles of key signaling networks in choanoflagellates, single - celled organisms that are the closest living relatives of animals.

The team demonstrated that GPR158 affects key signaling pathways involved in mood regulation in the region of the brain called prefrontal cortex, though the researchers emphasized that the exact mechanisms remain to be established.

Janus kinases carry out important intracellular functions in many organs — for instance, activating key signal pathways in the systems which form new blood cells.

The stem cells reside in unique micro-environments, so - called niches which provide key signals that regulate stem cell self - renewal and differentiation.

But Lonard and O'Malley had a counterintuitive idea: what if they could disrupt key signaling pathways and kill cancer cells by overstimulating SRCs?

Her main research interests lie with investigating key signaling mechanisms in retinal pigment epithelium, with the focus on the pathway mediated by mechanistic target of rapamycin (mTOR), and to identify molecular targets that can potentially be translated into interventional targets for treating chronic ocular diseases such as AMD.

This screening model was validated during our collaboration with the pharmaceutical group Roche and had revealed key signalling pathways involved in the control of NSC self - renewal (see Georges et al., 2015).

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Members of the steroid receptor coactivator (SRC) family of oncogenes are especially promising as therapeutic targets because these proteins sit at the nexus of key signaling pathways that cancer cells use to quickly grow, spread to other tissues, and acquire drug resistance.

The group went on to identify three key signalling networks that were represented by the bCSC DMR - associated genes; NFKB RB1 and TGFB1, and then analysed these networks in various breast tumours.

We have identified several transcription factors and components of key signaling pathways that are highly expressed in pluripotent epiblast cells of the developing human embryo.

Another key signal is coming from insiders at gold companies.

Consider these key signals.

Further, U.S. unemployment rates remain low nationwide, a key signal for the borrowing economy.

That monstrous uptick in volume was a key signal because it clearly pointed to institutional accumulation, which acts as a gas pedal that powers the best stock breakouts.

In particular, the market saw the increase in the median number of expected interest - rate hikes in 2017 — an increase from 2 to 3 — as the key signal showing the Fed was preparing to take even more aggressive action in the near future.

Many economists said a key signal of the economy's health in the second half of 2013 will come from Friday's report on consumer spending in July.

To summarize his argument, the rational for seeking low volatility dividends stocks is that «Volatility is considerably persistent through time, and the implied volatility from options prices is a key signal for determining the probability of corporate distress.The higher the implied volatility, the higher the probability of distress.

If you remember how the 2008 financial crisis unfolded, one of the key signals was the soaring TED spread... the spread between the risk free T - Bill interest rate and the overnight rate charged to corporate borrowers in the Eurodollar market.

It uses a complex algorithm to factor everything in and then looks for key signals that tell it to place a trade.

Further, under these circumstances infant crying is a key signal that engages mothers and therefore may assist in the emerging social and emotional development of the infant.

While it's largely arbitrary when the budget is approved, Cuomo has made it a key signal of the government functioning under his watch.

Eventually, however, she realized that swearing can actually be a key signal of how serious things are on the ground.

By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder.

They were interested in one of the cell's key signaling pathways, the MAPK pathway, which helps control cell growth, embryonic development, and the maturation of oocytes into eggs.

They also identified a key signaling molecule, an enzyme called Rho that stimulates stem cells to turn bone - like.

More importantly, Choudhury and colleagues found that DAZAP1 directly links the regulation of gene splicing with the MAP kinase pathway — a key signaling pathway that controls cell proliferation.

Specifically, the paper shows that a key signaling molecule, EIN2, is an essential component in the ethylene - response process.

Specifically, the study published in the May issue of Nature Immunology and led by La Jolla Institute Professor Shane Crotty, Ph.D., and Instructor Kok - Fai Kong, Ph.D., reported that an enzyme called TANK - binding kinase 1 (TBK1) controls the maturation of antibodies by associating with a key signaling molecule known as Inducible T cell Co-Stimulator or ICOS.

In their latest study, researchers at La Jolla Institute for Allergy and Immunology identified a key signal that drives the commitment of immature Tfh cells into fully functional Tfh cells and thus driving the step - by - step process that results in a precisely tailored and effective immune response.

«We discovered that male zebrafish have a very important set of structures on their pectoral fins that they use for breeding and that these structures secrete a potent molecular inhibitor of a key signaling pathway to aid their cycles of regular replacement,» explains senior author Kenneth Poss of Duke University Medical Center.

In a paper published in the 8 January issue of Nature, scientists report that calcium ions are a key signal that helps an embryo tell its left from its right, a process that determines where the asymmetric organs such as the heart and liver are placed.

Their focus was on ubiquitin, a key signaling molecule in this process.

The absence of a key signaling protein in the brain during infancy could lead to anxiety disorders later in life, scientists say.