Sentences with phrase «kidney structures»

In addition, the findings may help guide emerging stem cell - directed technologies to generate normal kidney structures for studying and treating human kidney disease.

«Investigators create complex kidney structures from human stem cells derived from adults: New technique offers model for studying disease, progress toward cell therapy.»

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.

Investigators at Brigham and Women's Hospital (BWH) and the Harvard Stem Cell Institute (HSCI) have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

«We have converted skin cells to stem cells and developed a highly efficient process to convert these stem cells into kidney structures that resemble those found in a normal human kidney.

The results, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to new avenues for research into the processes that direct cells to form functional kidney structures.

At the end of 2013, they reported the successful creation of an in vitro three - dimensional kidney structure from human iPS cells.

«The information will guide translational approaches to model and treat kidney disease, and engineer new kidney structures to restore kidney function.»

Overall, stem cell invasion of the biomaterial helped to regenerate kidney structures such as glomeruli (synaptopodin and CD31 positive) and tubules (cytokeratin and neprilysin positive) and promote recovery of function.

An ultrasound study will be valuable in demonstrating how much normal kidney structure remains.

The kidney structures formed could be used to study abnormalities of kidney development, chronic kidney disease, the effects of toxic drugs, and be incorporated into bioengineered devices to treat patients with acute and chronic kidney injury.

The kidney structures also have the potential to facilitate further studies of how abnormalities occur as the human kidney develops in the uterus and to establish models of disease where they can be used to test new therapies.

The P: Cr test is not helpful when your pet is dehydrated, when the protein source is somewhere in the kidney structure itself, when the urine contains blood (visible or not), or when the pet has a urinary tract infection.