Sentences with phrase «liver tumors»

There is a slightly increased risk of primary liver tumors in male dogs.

The mice with such damage subsequently suffered more and larger liver tumors induced by other chemical exposures.

A virus that has shown promise as a vector for human gene therapy causes liver tumors in neonatal mice.

And in 2001, molecular biologist Mark Sands at Washington University in St. Louis, Missouri, found a high rate of liver tumors in middle - aged mice that had been treated as newborns with a supposedly safer viral vector.

Synchronous resection of primary colorectal tumors and metastatic liver tumors is safe and effective in patients who require only minor liver resections.

Steroid abuse has been associated with liver tumors and a rare condition called peliosis hepatis, in which blood - filled cysts form in the liver.

«And thus, maintaining internal physiological homeostasis is really important for liver tumor suppression.»

Hepatocellular carcinoma is the most common primary liver tumor in dogs.

I have recently been on my most tumultuous life adventure yet... on this one I was fighting a huge monster, a one pound, 13 ounce cancerous liver tumor!

«We were excited to see that in human liver tumors mTORC1 signaling correlates with FGF21 expression,» comments cell biologist Dr. Marion Cornu and first author of the study.

«New MRI approach detects early liver tumors in mouse model of human disease.»

UC San Diego Medical Center is the first hospital in the region to offer microwave technology to destroy liver tumors.

At the Solid Tumor Oncology Program, part of C.S. Mott Children's Hospital at the University of Michigan, we provide comprehensive, multidisciplinary care for children with hepatoblastoma and other liver tumors such as hepatocarcinoma, hepatic adenoma and hamartomas.

When injected with anti-cancer drugs directly into the tumor, scientists saw «markedly suppressed liver tumor growth as well as prolonged survival time... with little toxicity.»

Gene therapy researchers have found that a popular viral vector used to insert disease - curing genes into mice has a dangerous down side: it can apparently trigger liver tumors.

With the brake on T cells, liver tumors formed and grew in the chronically inflamed mice.

Mice exposed to triclosan for six months (roughly equivalent to 18 human years) were more susceptible to chemical - induced liver tumors.

Experiments showed that mice unable to produce AIM fed on a high - fat diet for a year developed multiple liver tumors.

Analysis of liver tumor samples from patients showed that NRF2 expression correlated with tumor metastasis.

Other published data have already shown that FXR - deficient mice spontaneously develop steatohepatitis and liver tumors even when they are fed a normal rodent diet.

Their study in an animal model is an essential step toward creating tools to improve liver tumor detection in human patients — whether primary liver cancer or metastatic tumors that have spread from other organ sites.

The researchers designed a modification in the chemistry of the ProCA32 MRI contrast agent so detectable metals form a bond with calcium molecules on proteins specific to liver tumor tissue.

Scientists at Georgia State University (GSU) with funding from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have designed an imaging technique to detect early - stage liver tumors, and have proven it successful in mice.

These results clearly indicate that the expression of DDX3 is down - regulated in liver tumor cells.

She has published journal articles and book chapters on topics including canine osteosarcoma, canine and feline liver tumors, and canine and feline plasma cell cancer / multiple myeloma.

But this can not be taken as a very sharp indicator of hepatocellular carcinoma because serum levels of fetoprotein are usually elevated in other types of liver tumors like bile duct carcinoma, lymphoma and non-neoplastic hepatic disease.

Metastatic liver tumors are generally multiple nodules.

In mice that lacked tumor - fighting cytotoxic T cells, 27 percent of 15 mice had large liver tumors at six months.

the most common primary liver tumor is the hepatocellular carcinoma which invades into the liver tissue.

Researchers gave animal models an oral supplement of spermidine and found that they lived longer and were less likely than untreated individuals to have liver fibrosis and cancerous liver tumors, even when predisposed for those conditions.

Activated mTORC1 signaling (top) correlates with increased FGF21 expression (below) in human liver tumor.

«The authors have shown a very sensitive and specific way of distinguishing the disease process within a healthy liver and have found a characteristic molecular signature that indicates the presence of an early liver tumor,» explained Richard Conroy, Ph.D., director, Division of Applied Science & Technology, NIBIB.

Surgery — the standard therapy for treating hepatoblastoma and other liver tumors is surgery to remove the tumor.

Dietary 2asa prevents the development of liver tumors caused by the peroxisome proliferator WY - 14,643.

Before that, the boy was treated for seizures and had two rounds of chemotherapy for a liver tumor that eventually warranted a liver transplant last summer.

Cells that are able to shut down the activity of miR - 483 and miR - 551, the researchers found, increase production of an enzyme known as CKB, which can help the cells convert compounds found abundantly in the liver tumor environment into an energy source.

They injected both the knockout mice and normal mice with AAV vector and found that 33 % -56 % had liver tumors, compared to 4 % -8 % of untreated mice.

Although the EPA has classified DDT and its metabolites, DDE and DDD, as «probable human carcinogens,» and although mice exposed to DDT for more than a year did develop liver tumors, a detailed analysis of multiple studies of breast, pancreatic, prostate, testicular, and other forms of cancer in people led the authors of the ATSDR report to conclude that «there is no clear evidence that exposure to DDT / DDE causes cancer in humans.»

Mice that inhaled cumene fumes developed lung tumors and liver tumors, according to HHS's review.

Mice lacking a receptor called CAR that regulates bile acid breakdown and is also known to promote liver cancer, did not get any liver tumors.

The study builds on recent work by Tyler Jacks, the director of the Koch Institute, who has also used CRISPR to generate lung and liver tumors in mice.

In animal tests, p - dichlorobenzene causes kidney and liver tumors.

She also conducts clinical research evaluating prognosticators of outcome in patients with liver, bile duct and liver tumors and investigates new imaging agents in pancreas and liver cancers.

Together, our results suggest that the decreased expression or loss of nuclear localization of DDX3 may play a regulatory role in the formation of liver tumor and cutaneous SCC.

Interestingly, the mRNA expression of DDX3 was declined in the liver tumor specimens (three of three samples) and SCC of the vulva (three of five samples; Supplementary Fig.

Dr. Kamran Idrees» primary interests are in GI, liver and pancreaticobiliary malignancies including, peritoneal surface malignancies, colorectal cancer, gastric cancer, pancreatic tumors, liver tumors (primary and metastatic), gallbladder cancer, cholangiocarcinoma, retroperitoneal sarcomas and gastro - intestinal stromal tumors (GIST).

Chronic inflammation resulting from infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) promote the development of liver tumors.

In addition to our expert gastrointestinal oncology team, a Pancreatic Cancer Clinic and a Liver Tumor Clinic offer specialized integrated care, research protocols, and supportive services for patients.