Sentences with phrase «loss of function»

A brain injury can cause loss of function in one or more of the above areas.

This leads to the gradual deterioration of the hip joint's integrity and eventually leading to a complete loss of the function of these joints.

As this happens, the cat starts to show signs associated with loss of these functions, such as lethargy and weight loss.

Body mobility — Extensive trauma may result in a permanent loss of function, including speech and language abilities and the ability to perform bodily functions independently.

Chronic renal failure is the gradual loss of function of the kidneys, most frequently in older pets.

It depends on how much loss of function there is.

The variant has been found in two men with prostate cancer, and in vitro analysis suggests it causes a partial loss of function of the gene.

This depends on how much loss of function there is.

Either form of paralysis can be complete (total loss of function and sensation below the injury) or partial.

When taken in conjunction with other natural substances it also shows promise as a treatment for the pain, stiffness, and loss of function associated with arthritis.

Gradually but progressively our bodies begin to function less effectively, and that increasing loss of function makes us more vulnerable to disease and death....

In that situation, sluggish blood flow through the kidneys leads to kidney loss of function and can be responsible for mild - to - moderate protein leakage into the pet's urine.

By then, signs can be present that reflect loss of function of the liver, kidneys, bone marrow, and nervous system.

As you can imagine, a 2/3 loss of function in the kidneys is a huge problem, and it can't be reversed.

While many types of soft - tissue injuries heal on their own, some are much more - serious and can lead to permanent loss of function.

A cat that is having difficulty breathing or has loss of function of hind or front limbs requires veterinary care as soon as possible.

The mutant mice displayed the same symptoms as HED patients with severe loss of function mutations in the WNT10A gene.

Injuries to the spine in the mid-back may cause loss of function in the lower body, including temporary or permanent paralysis.

Phloem translocation is definitely interfered with during attack, although the proportions of the eventual loss of function due to adult vs larval feeding is not clear to me.

It can have several different causes, all involving loss of function of a metabolic pathway that moderates levels of an organic compound called methylmalonic acid.

It can cause acute pain and various clinical signs such as loss of function of the hindlimbs (most commonly, although other organs or limbs can be affected).

For the Dscam loss of function experiment the dscam05518 allele was used [22].

The author of this open access review of the study of growth hormone in aging is one of the eminent experts in this part of the field, noted for work on various loss of function mutant mice, lacking either functional growth hormone or functional growth hormone receptor genes.

It can come on suddenly, apparently without any warning and can result in impaired motor function, a wobbly gait or most often, complete loss of function in the hind limbs.

Patients with A-T begin life with neurological deficits that become devastating through progressive loss of function in a part of the brain called the cerebellum, which leads to severe difficulty with movement and coordination.

Some diseases are associated with vessel leakage and accompanying edema, which can lead to severe loss of function.

To localize the source of his seizure and identify which nearby tissue could be surgically removed without major loss of function, Parvizi's team implanted so - called subdural intracranial electrodes into Blackwell's brain that would not only monitor neuronal activity but could also apply electric current and so stimulate the adjacent part of the brain.

Examples of findings during medical evaluations which could substantiate allegations of torture include scars compatible with whipping, an injury to the arms known as brachial plexus palsy causing significant loss of function, and bone fractures.

Hip Dysplasia: an inherited disorder that results in improper hip joint development and eventual loss of functioning in the hip joints.

Rather than discard the bandage, immortalising the object in this way allows it to survive as a memory of an incident, which was overcome and highlights the contradiction between its previous use to heal and its subsequent loss of function.

Soft Tissue Damage This type of injury is characterized by pain, swelling bruising and potential loss of function after damaging muscles, ligaments and tendons throughout the body.

The Czech Centre for Phenogenomics (CCP), through its membership in INFRAFRONTIER and IMPC, is a partner in a collective global network that aims to comprehensively and systematically analyze the effect of loss of function gene mutations in mice.

This secondary injury amplifies the original wound and the corresponding loss of function, creating a true dead area in the spinal cord that defies rehabilitation.

There are a few support aids that can recapture the loss of muscle function in the arms, but these support aids do not compensate for the entire loss of function and can result in stigmatisation.

Hair thinning in a human patient and mouse with inherited loss of function mutations in WNT10A is shown.

«We have successfully developed the first mouse model for Alix that allows us to study the consequences of Alix loss of function in vivo.

Unlike for ccr5, there are no known humans with loss of function cxcr4 mutations that would provide insight into the safety and viability of cxcr4 disruption in mature CD4 + T cells.

Finally we aim at identifying phenotype specific transcriptional targets of mutant HTT (mut - HTT) or HTT loss of function in relevant neuronal / glial populations.

I will discuss our latest results showing that satellite cells in their homeostatic quiescent state are equipped with quality control mechanisms to preserve their fitness, and how age - associate alterations in these protective mechanisms lead to stem cell loss of function and regenerative capacity.

HDL from ApoA1 Transgenic Mice Expressing the 4WF Isoform Is Resistant to Oxidative Loss of Function.

CR can lower the prevalence of age - related loss of function and multiple diseases, including tumors, cardiovascular disease, neurodegeneration, and protects against diabetes, cancer, cardiovascular disease, sarcopenia, and neurodegeneration of certain brain regions in rhesus monkeys (31).