Sentences with phrase «lung metastasis»

Immunological Invisibility Cloak Among them is Joel Linden, Ph.D., who recently reported that jamming signals transmitted by membrane proteins called adenosine receptors, which are expressed on T cells and on specialized cell - killing cells called NK cells, made both cell types more effective in halting lung metastasis of melanoma cells.

Based on the mouse findings, the team classified the patients as high or low risk for lung metastasis.

In the orthotopic breast cancer model around 12 % of tail injected iPSC - EPCs homed to the mammary pad region, while in the breast cancer lung metastasis model iPSC - EPCs were distributed predominantly to the lung region.

«We determined that it was specifically fructose, in table sugar and high - fructose corn syrup, ubiquitous within our food system, which was responsible for facilitating lung metastasis and 12 - HETE production in breast tumors.»

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

LJI's Catherine Hedrick, Ph.D., recently discovered that a population of white blood cells called «patrolling monocytes», protects against lung metastasis.

Oral administration of mebendazole in mice elicited a strong antitumor effect in a subcutaneous model and reduced lesions in experimentally induced lung metastasis without any toxicity when compared with paclitaxel - treated mice [9,20].

To do so, they injected melanoma cells into the bloodstream of normal or E2 mutant mice and monitored lung metastasis.

Curcumin suppresses the paclitaxel - induced nuclear factor - kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

Over half of the cases will have bony invasion and lymph node metastasis at the time of presentation and approximately 15 % will have detectable lung metastasis.

«We determined that it was specifically fructose, in table sugar and high - fructose corn syrup, ubiquitous within our food system, which was responsible for facilitating lung metastasis and 12 - HETE production in breast tumors.»

Tumor staging for TCC includes radiographs («x-rays») of the thorax to look for lung metastasis, radiographs and ultrasound (or CT scan) of the abdomen to look for metastasis in the abdomen and to assess any changes in the kidneys that result from obstructed urine flow, and imaging of the bladder to determine the exact location and size of the tumor within the bladder (see Figure 1).

The sum of metastatic tumor volume was first calculated from four lobes of lungs per animal (see Materials and methods), and the lung metastasis per group is presented as tumor volume (cubic millimeters).

Utilizing this model, we found that the benefit of removal of the primary breast cancer in Stage IV disease depend upon the tumor burden (Rashid OM et al, Surgery 2013), and we also found that the lung metastasis model by tail vein injection of cancer cells is genetically similar to lung metastasis tumor from breast tumor (Rashid OM et al, Journal of Thoracic Disease 2013).

Finally, to determine whether LARP7 KD also results in an increase in breast cancer metastasis in vivo, the T47D control or shLARP7 - 2 cells were injected intravenously into the nude mice, and lung metastasis was examined 12 weeks later.

The goal was to see if we can slow or stop the formation of lung metastasis (spread of tumor to your dog's lungs which occurs in over 90 % of cases).

Ideally, the lung metastasis, or the spread of the tumor to the dog's lungs (which occurs in more than 90 percent of osteosarcoma cases), will be slowed or stopped entirely by these NK cells.