Sentences with phrase «lysosomal function»
Lysosomal function refers to the ability of lysosomes, which are small structures inside cells, to perform specific tasks. Lysosomes act as the cell's recycling centers and waste disposal units. They break down waste materials, damaged organelles, and foreign substances, clearing them out of the cell. Additionally, lysosomes are involved in the digestion of nutrients and the removal of harmful bacteria. Overall, lysosomal function is crucial for maintaining a healthy cell and proper functioning of the body. Full definition
Elizabeth B. Moloney, PhD, is a post-doctoral research fellow at the Neuroregeneration Research Institute at McLean Hospital, where she is involved in developing both in vitro and in vivo approaches for understanding the role of lysosomal function in the pathophysiology of cellular aging and...
mcleanhospital.org
Type 1 Diabetes: Urinary Proteomics and Protein Network Analysis Support Perturbation of Lysosomal Function.
That depression in turn weakened overall lysosomal function and contributed to degeneration of neurons.
Building on these extreme examples that emphasize the potential roles played by healthy lysosomes in protecting neurons against the age - dependent accumulation of toxic cellular debris, we ultimately seek to understand how neurons sense and regulate the status of their lysosomes, how lysosomes are affected during age - related disease states and whether lysosomal function can be modulated for therapeutic purposes.
Both MPS IIIA and GM1 are classified as neuropathic (i.e. affecting the central nervous system) Lysosomal Storage Disorders, a group of approximately 50 rare inherited metabolic disorders that result from defects in lysosomal function.