Sentences with phrase «molecular approaches»

Most recently, Sasha's work has focused on a central role for Tregs in cancer treatment, suggesting that finessing the action of Tregs using molecular approaches could help enhance the efficacy of cancer immunotherapy drugs, which work by unleashing the immune system against tumors.

Queen's University Belfast are seeking candidates whose research focuses on innovative molecular approaches to investigate viral mechanisms of immune evasion and alteration of cell signalling.

By the early 1980s, Columbia University had begun to emerge as a pioneering center for molecular approaches to the study of brain function.

In the future, studies are aimed at using novel molecular approaches to selectively delete AMPK in specific brain regions associated with nicotine dependence to better understand the functional role of this protein in addiction.

We've used modern molecular approaches to characterize the vaginal microbiome and link specific bacteria to HIV acquisition risk in young women living in Sub-Saharan Africa, where HIV is most profound,» says first author Christina Gosmann, a postdoctoral research fellow at the Ragon Institute of MGH, MIT and Harvard.

Their research, described in the Journal Neuroscience, provides new insight into protective mechanisms for hearing loss and suggests the potential for future molecular approaches, which may include gene therapy or medicine, to treat ARHL and NIHL.

K. J. Peterson, R. A. Cameron, K. Tagawa, N. Satoh, E. H. Davidson, A comparative molecular approach to mesodermal patterning in basal deuterostomes: The expression pattern of Brachyury in the enteropneust hemichordate Ptychodera flava.

To understand how vision is shaping single species and whole communities, I'm using a variety of methods including NGS molecular approaches coupled with transgenesis experiments, neurophysiological assessments of visual systems and behavioural experimentation.

They are seeking candidates whose research focuses on innovative molecular approaches to investigate viral mechanisms of immune evasion and alteration of cell signalling.

By using a combination of advanced genetics, molecular approaches, and microscopy techniques, they found that this signaling pathway is used in the adult brain in a completely novel way.

These are at length / time scales intermediate between the CHEMICAL BIOLOGY AND BIOPHYSICS IRG and the MOLECULAR APPROACHES TO CELL FUNCTIONS AND INTERACTIONS IRG.

«To better understand safety issues, we are making efforts to employ more modern investigational, molecular approaches to safety assessment — and increase our safety testing work force by about 10 percent,» says Phil Bentley, vice president and global head of preclinical safety at Novartis Institutes for BioMedical Research in New York City.

Using both biophysical and molecular approaches, the researchers have shown, for the first time, that zebrafish regenerates its caudal fin by a process that involves a specific channel in the cell membrane, called V - ATPase, that pumps hydrogen ions (H +) out of the cells generating an electrical current.

We used anatomical and molecular approaches to demonstrate expression of the 5 - HT3A subunit in taste ganglia and taste buds and then used physiological and pharmacological approaches to determine whether these receptors are functional and crucial in the taste system.

Contributions that use cellular and molecular approaches to shed light on mechanisms of physiological control at higher levels of organization also appear regularly.

We exploit chick and mouse embryo animal models, combined with live imaging, cell and tissue cultures and molecular approaches.

Using single - molecule imaging, super-resolution microscopy and various biophysical and molecular approaches she will explore how gene expression in living cells works.»

Cellular and molecular approaches are pivotal and have long been employed in medicine and clinical research.

Sander M, Bergersen LH, Storm - Mathisen J (2009) Molecular approaches to understanding neural network plasticity and memory: the Kavli Prize Inaugural Symposium on Neuroscience Neuroscience, 163 (4), 965 - 76 PubMed 19664741

Using systems, cellular and molecular approaches, they investigate how risk factors contribute to neurodegeneration and test new treatments.

Over the past decade, we have used computational and molecular approaches to annotate mi / si / piRNAs, and to elucidate mechanisms of how they are made and how they are sorted into appropriate Argonaute effector complexes.

Using a comprehensive integration of genomic and molecular approaches we will determine the biochemical context in which AR signaling drives breast cancer tumorigenesis.

The aim of the molecular approach is to identify a potential genetic test that either helps breeders avoid the expression of the phenotype in their pups, or informs better treatment options.

From how severe flooding is affecting lives in New Brunswick; to the inside story of Operation Medusa, a pivotal moment for the Canadian military; to the molecular approach to cooking... This is The Current.

In this study, we used a molecular approach to identify...