In a phase II trial described in The Lancet today, Ionis and academic collaborators report that it extended the life spans and improved the motor function of babies with severe SMA, compared with the disease courses in
natural history studies of untreated babies.
Analysis of this data revealed a set of candidate biomarkers which were then tested against over 150 longitudinal samples from an
SMA natural history study by the Pediatric Neuromuscular Clinical Research Network.
SMA Foundation Patient Advisory Board member Amelie Gubitz finished the discussion by suggesting these issues be followed
in natural history studies.
A new Florida Museum of
Natural History study offers the first comprehensive overview of the surprisingly complex question of when butterflies and moths are active.
Sam Droege of the US Geological Survey and Sean Brady of the Smithsonian's National Museum of
Natural History study native bee populations on the base.
Since Darwin: The Evolution of Evolution Smithsonian National Museum of
Natural History Study Darwin and his theory of evolution, then find out how the thoughts and ideas of evolution have changed since his time.
I am presently working at the American Museum of
Natural History studying primate ecomorphology by collecting functional measurements on post-crania of extant primates.
Through regional networks in the U.S. like the Pediatric Neuromuscular Clinical Research (PNCR) Network and Project Cure, and international organizations such as the International Coordinating Committee (ICC) and TREAT - NMD, the SMA community has collaborated effectively on recruiting patients, establishing standards of care, standardizing outcome measures, and supporting multi-site clinical efforts, such as the Biomarkers for SMA (BforSMA) and the PNCR
Network Natural History studies.
Both Easterson and Jerimijenko's projects point to the difficulties in
conventional natural history studies of noting where «natural» habitats and behaviors end and the human world begins, if in fact they can be separated.
In one
natural history study of 55 untreated US patients with early Lyme disease associated with erythema migrans, 34 (62 %) developed objective signs of arthritis, 10 (18 %) developed arthralgias without arthritis, but 11 (20 %) remained completely well over a mean follow - up of 6 years [2].
The Pediatric Neuromuscular Clinical Research Network will launch with
a natural history study of patients suffering from spinal muscular atrophy.
Studies to improve the knowledge of genetic diseases include
the natural history study for MLD, advanced diagnosis and natural history of primary immunodeficiencies and immunedysregulatory disorder, and immune reconstitution after hematopoietic stem cell transplantation for genetic disorders.
SMA
Natural History Study The PNCR Network helped to characterize the SMA patient population and increase understanding of the stages of disease progression through the ongoing greater than 24 month SMA Natural History Study (NHS).
She has focused on expanding the expert disease community of healthcare professionals, patients, industry and regulators; building disease registries and
natural history studies; developing consensus care guidelines; and developing strategies to improve the quality of diagnosis and patient care.
Of all of the volumes in Pennsylvania Hospital's Historic Library, Stacey Peeples, the hospital's curator - lead archivist, said her favorites are the botanical and
natural history studies.
Although this study began with a focus on child care, it has evolved to
a natural history study of children.
He was impressed with the extraordinary importance of the islands for
natural history studies and urged the park service to accept a land transfer.
His interest ranges from folk embroidery, made on vintage fabrics taken from his mother's chest, to
natural history studies and specimens under glass; from drawings, seemingly childish and clumsy and made in response to familiar situations to elements of Russian culture, scattered around the exhibition space and combined with memories of the local context.