Sentences with phrase «new therapeutic approaches»
The aim is to identify the genetic causes, understand the pathology, prevent the transmission and, finally, develop new therapeutic approaches for these devastating often fatal disorders.
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In the long term, however, these findings could contribute to the development of new therapeutic approaches.
This discovery makes it possible to screen for the disease, and opens the door for potential new therapeutic approaches.
Our objective is to devise new therapeutic approaches for the treatment of respiratory infections.
The results of the research open new possibilities for understanding the cellular mechanisms responsible for genome instability and for being able to explore new therapeutic approaches.
I can also leverage my broader knowledge of physiology to think about new therapeutic approaches and translation.
Understanding disease biology through basic research accelerates the identification of new therapeutic approaches.
Beyond the potential for new therapeutic approaches in treating MDS or AML, the paper revealed a new and critical immune - related function for TRAF6, according to the authors.
This change, known as somatic copy - number alterations, may be key to disease progression and might offer new therapeutic approaches for ovarian cancer and other malignancies.
Jan. 26, 2018 — New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches.
We are now using these technics starting from patient - derived PSC to increase our understanding and try to find new therapeutic approaches for devastating neurodevelopmental disorders.
Prof. Gabriele Bergers (VIB - KU Leuven): «Understanding the underlying mechanisms of the process will contribute to the overarching goal of developing new therapeutic approaches to boosting the immune system in tumors.»
In the next step, he and his team aim to investigate how MDSCs normally terminate inflammation, and hope to use this knowledge to devise new therapeutic approaches against inflammatory skin diseases like neurodermatitis.
It is exciting to see this work evolve into new therapeutic approaches.»
Defining the molecular changes in the striata of Parkinson's diseased brains is necessary to better understand the disorder and design new therapeutic approaches for its treatment.
The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes controlling whether or not genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.
The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast cancers more aggressive and resistant to chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome by preserving p53 levels.
The conference aims at bringing together international experts from different fields of cancer research to present and discuss new therapeutic approaches regarding different tumor entities as well as new findings in the field of tumor biology seeking to incorporate innovative platforms into cancer research.
The conference aims at bringing together international experts from different fields of cancer research to present and discuss new therapeutic approaches regarding different...
The study also reinforces the potential value of brain scans for identifying and understanding schizophrenia in individual patients, for finding promising new therapeutic approaches, and for helping clinicians track a patient's progress during therapy.
«So, the idea of discovering new therapeutic approaches for anxiety or depression may not be so far - fetched,» says Peterson.
«The research suggests a possible new therapeutic approach to autoimmune disorders that would be designed to boost the function of regulatory T cells by modulating cell metabolism,» Chi said.
A new review published in Digestive and Liver Disease looks at these findings and provides insights into potential new therapeutic approaches using antifungals and probiotics in the treatment of inflammatory bowel diseases (IBD) such as Crohn's disease (CD).
«This mechanism may offer the potential to develop an entirely new therapeutic approach,» says C. Ronald Kahn, M.D., Joslin's chief academic officer, Mary K. Iacocca Professor of Medicine at Harvard Medical School and senior author of a paper on the research published in the journal Nature.
These findings could help to develope new therapeutic approaches towards genetic diseases.
The work of Dr. Diaz - Meco in this area is being pursued further from that drug discovery point of view in a project in collaboration with the SBP Chemical Genomics group, and structural biologist at Scripps, with the goal of identifying potentially new therapeutic approaches to the selective inhibition of mTORC1 in cancer.
«It's still very early in this safety study, but this could be an exciting new therapeutic approach for people who have just suffered a stroke,» said Sean Savitz, M.D., assistant professor of neurology at the medical school and the study's lead investigator.
Professor Nizetic, calling for further research into the components of the disturbed cascade he and his team have revealed said; «We hope that further research might lead to clues for the design of new therapeutic approaches tackling developmental delay, mental retardation, ageing and regeneration of brain cells, and Alzheimer's disease.
If the same goes for humans, it could spell a new paradigm for recharging our aging brains, and it might mean new therapeutic approaches for treating dementias such as Alzheimer's disease.»
This finding opens up the question whether intermittent fasting alone or in combination with a pharmacological agent could serve as a useful new therapeutic approach for treating pain.
``... in order to better understand the pathogenesis of AD [Alzheimer's Disease], to study and to monitor the activity and the efficacy of new therapeutic approaches such as KD [Ketogenic Diet] and, finally, to develop a personalized management of the disease».
Ceva opened the way to a completely new therapeutic approach to help manage behavioral issues in pets.
As a relatively new therapeutic approach, founded by Drs. Sue Johnson and Les Greenberg, EFT draws on attachment theory.
North Carolina is rich in both natural resources and expertise in natural products drug discovery, and with recognized leaders in the fields of infectious disease, inflammation, allergy and pain, NC State's CMI has a unique opportunity to apply innovative academic research to address the urgent need for new therapeutic approaches in these areas.
«Collateral» lethality may offer new therapeutic approach for cancers of the pancreas, stomach and colon.»
«Antifungals and probiotics may play a key role in the development of treatment for Crohn's disease: Potential new therapeutic approaches for inflammatory bowel diseases may involve using antifungals with probiotics.»
Find new therapeutic approach to halt or to cure muscle atrophy are our main objectives regardless of etiology.
«Against the background of these findings, we can, for example identify possible risk groups and develop new therapeutic approaches,» adds Dr. Christian Gieger (HMGU).
We hope to design new therapeutic approaches to suppress the deregulated immune response in inflammatory diseases.
Dr. Paul R. Sanberg, Distinguished University Professor, a co-author of the paper, concluded that «these novel data showing BSCB damage in subacute and chronic ischemic stroke may lead to development of new therapeutic approaches for patients with ischemic cerebral infarction.»
This study could open up the possibility of finding ways to turn this activity on and off, making way for new therapeutic approaches for hard - to - treat diseases, Wu said.
«The results suggest that this new therapeutic approach is safe and provides good visual outcomes,» says Lyndon da Cruz, consultant ophthalmologist at Moorfields Eye Hospital NHS Foundation Trust.
A new study in The American Journal of Pathology offers insights into the cellular aging that may trigger excessive fibrosis formation in the liver as well as possible means to inhibit these changes, which may lead to new therapeutic approaches for patients with ALD.
«Given this mechanism, ataluren offers the potential for a new therapeutic approach for multiple nonsense mutation genetic disorders by targeting the underlying cause of the disease.»
In precision medicine era legacy gifts of patient brain tissue reveal disease mechanisms and new therapeutic approaches
«This work represents a mechanistic insight that could lead to the development of a new therapeutic approach for preventing asthma.»
There are no approved drugs to treat Ebola virus or other filovirus infections, so there is a critical need for new therapeutic approaches.
Clinical trials will be required to establish whether these promising findings will translate into a new therapeutic approach for ALL.