Sentences with phrase «nuclear transfer»

Therefore, efforts are now being made to enable women with this disease to bear healthy children by means of nuclear transfer.

He'd never been able to get an adult frog by using nuclear transfer from an adult cell donor.

Successful nuclear transfer in dogs has been elusive until now because it is difficult to get egg cells to mature in the lab.

None came to term, but one lived 29 weeks in the womb, long enough to suggest that the procedure, known as nuclear transfer, is viable.

Scientists understand relatively little about these on - and - off switches in normal cells, however, let alone the unusual reversal that takes place during nuclear transfer.

But the experiments failed, he says, because nuclear transfer was too inefficient to produce the needed cells.

«We are pleased that human embryos can continue to be generated through somatic cell nuclear transfer for the production of human embryonic stem cells,» says Justin St. John, director of the Centre for Reproduction and Development at the Monash Institute of Medical Research in Victoria.

If ES cells could be a source of human oocytes, scientists might be able to use them for nuclear transfer experiments rather than using eggs from human donors, which are in short supply.

This bill (S. 1602) outlaws the implantation of human embryos created by nuclear transfer technology, not the technology itself.

Pharming is interested in using a potentially more efficient method called nuclear transfer to clone cows, because the technique could speed the process of growing herds that reliably produce drugs in their milk.

The bill calls for steep fines and prison sentences of up to 10 years for anyone convicted of using somatic cell nuclear transfer technology to clone humans.

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

For example, nuclear transfer experiments in dairy cows, says Robl, suggest «there is a significant difference in milk production that could be attributed to the [recipient] cytoplasm.»

Outline title: «First live birth using human oocytes reconstituted by spindle nuclear transfer for mitochondrial DNA mutation causing Leigh syndrome» by J. Zhang et al. published in outline form by the American Society of Reproductive Medicine's Fertility and Sterility journal website.

It quotes him further as admitting that, «I decided a few weeks ago not to pursue nuclear transfer [the method by which Dolly was cloned]» — and that the new approach is «easier to accept socially» — perhaps a partial fruit of contemporary pro-life efforts to keep the moral issue alive.

Alan Colman, research director, PPL: I had come from a background of nuclear transfer with John Gurdon [a developmental biologist at the University of Cambridge, UK].

The result «brings nearer the human benefits from nuclear transfer work,» says Ron James, managing director of PPL.

The Effect of Somatic Cell Nuclear Transfer on the Stability and Regulation of X Chromosome Inactivation

Scientists, with practice, have now been able to make nuclear transfer nearly routine to produce cattle, cats, mice, sheep, goats, pigs, and — as a Korean team announced in May — even human embryonic stem (ES) cells.

Then somatic cell nuclear transfer generated pig embryos carrying this genetic alteration.

DeGette's confusion about somatic cell nuclear transfer dovetails nicely with one of Levin's earlier points.

Roslin Bio-Med is the firm established to commercialize nuclear transfer, the method researchers at Roslin Institute used to clone Dolly the sheep in 1997.

«Advanced Cell Technology has the ability to produce transgenic animals using fetal fibroblast nuclear transfer,» claims Steve Parkinson, president and chief executive officer.

Nuclear transfer hinges on the fact that, somehow, factors in an egg cell's cytoplasm can reactivate all of the genes in adult cells so that they behave like stem cells.

So now let's look ahead: Fast - forward two generations from now, and I will contend that it will be possible, by medical advances, to make cloning [a child] by nuclear transfer safer than natural childbirth — that the cloned embryos will have a defect rate, let's call it, of less than 1 percent.

«We think that differentiation is a way that opens some doors and makes it easier for nuclear transfer programming to go back into embryonic stem cells.»

It is the first healthy, viable clone of an endangered species and the first successful birth from a cross-species nuclear transfer.

But PPL's Irina Polejaeva then added a second nuclear transfer to the cloning protocol: As soon as the transferred nucleus expanded, as it typically does, the PPL team removed that nucleus once again and placed it in another egg cell that had just been fertilized.

«We perform nuclear transfer for medical research.»

Ritchie: The simple way of describing nuclear transfer is that you take an oocyte, an unfertilized egg, and you remove the chromosomes.

To try to find a definitive answer, scientists led by George Daley of Children's Hospital Boston and the Harvard Stem Cell Institute in Cambridge, Massachusetts, compared the genetic signatures of mouse ES cells made through nuclear transfer and those made from parthenogenetic embryos.

To get around that problem, some researchers have tried nuclear transfer using a human cell and egg cells from rabbits or cows to produce so - called cytoplasmic hybrids, or cybrids.

Lanza's research focuses on the use of stem cells and regenerative medicine including nuclear transfer and stem cells in human transplantation.

While Gurdon's tadpoles did not survive to grow into adult frogs, his experiment showed that the process of specialization in animal cells was reversible, and his technique of nuclear transfer paved the way for later cloning successes.

The technique called somatic cell nuclear transfer became popular when Dolly the sheep, the first cloned mammal in 1997, was cloned using an egg to do the reprogramming trick.

«Using a variety of approaches the authors show that blastocysts generated by nuclear transfer do not differ from control IVF blastocysts.

There are lessons that we can learn from somatic cell nuclear transfer where the somatic cell brings accompanying mitochondrial DNA (mtDNA) into the egg.

«Nuclear transfer involves the reprogramming of adult, differentiated cells and persuading them to act like early - embryo cells,» said Dr Griffin.

Somatic cells can be reprogrammed either by nuclear transfer into oocytes or by fusion with embryonic stem (ES) cells.

One proposal that has received considerable scientific support has been to generate non-embryonic entities that can serve as a source of stem cells through a process termed Altered Nuclear Transfer (or ANT).

It won support in spite of two previous House votes to outlaw all forms of cloning, including research cloning (otherwise known as nuclear transfer), which scientists say is essential to realize the promise of ES cell research.

So Zhang took a different approach, called spindle nuclear transfer.

Dolly was created using nuclear transfer, a technique in which an intact donor cell is fused with an egg whose nucleus had been removed.

The majority of nuclear transfers in animals don't take, or they produce fetuses that abort at high rates, or they deliver creatures misshapen and sick.

The nuclei are inserted into egg cells which have had their original nucleus removed, a process called nuclear transfer.