Sentences with phrase «opiate receptors»

Given via injection or nasal spray, naloxone binds powerfully with opiate receptors in the brain, repelling the drugs the user has taken and sending him or her into an instant and painful withdrawal.

Uhl and crew then produced mice that had half the normal number of opiate receptors and as a result, experienced greater discomfort when exposed to a standard mildly painful stimulus.

PET scans have demonstrated that some individuals have twice as many mu opiate receptors in certain brain regions as others.

Independent of the brain effects already discussed, gliadin peptides may travel through the blood stream and can stimulate opiate receptors in the brain, resulting in their being termed gliadorphins, accounting for temporary withdrawal symptoms!

So, essentially what you're doing when you block opiate receptors is you cause the body to make more endorphins.

Snyder, who won a 1978 Lasker Award for identifying the brain's own opiate receptors, and his team have been studying the brain for decades.

And additional research has uncovered gender differences: women appear to have more kappa opiate receptors, which also bind with endogenous pain killers.

Looking at previous work on other addictions, such as alcoholism, we anticipated that pathological gamblers would have increased opiate receptors which we did not find, but we did find the expected blunted change in endogenous opioids from an amphetamine challenge.

Opiate receptor research has paid off both in fundamental understanding of brain function and in the development of novel therapeutic agents.

Opiate receptor subtype agonist - induced enhancements of sucrose intake are dependent upon sucrose concentration.

Studies compare grain consumption (and wheat in particular) with addictive substances, as wheat activates opiate receptors in the brain.

«I am honored that the Lasker Foundation has chosen this year to recognize the field of opiate receptor and opiate - like peptide research,» he said.

Independent of the brain effects already discussed, gliadin peptides may travel through the blood stream can stimulate opiate receptors in the brain resulting in their being termed gliadorphins.

Uhl and his colleagues, Ichiro Sora and Zaijie Wang, of Johns Hopkins University and the National Institute on Drug Abuse (NIDA) zeroed in on the gene encoding the mu opiate receptor — sections of which they first identified a decade ago.

Opiates, of course, are natural or synthetic substances that bind to opiate receptors in the brain, and are chemically similar to alkaloid compounds derived from Papaver somniferum, or the opium poppy.

Knockout mice, which completely lacked the gene and so manufactured no mu opiate receptors, were all the more sensitive.

«Among the many people who contributed to this area, my own special thanks go to Candace Pert who, as a graduate student, identified the opiate receptors in my laboratory.»

She was first to identify the opiate receptor, which was the first of the brain receptors to be found.

But it was Pert's supervisor, Solomon Snyder, who in 1978 shared the prestigious Albert Lasker Basic Medical Research Award with two scientists working in Scotland, Hans Kosterlitz and John Hughes, the first to isolate the enkephalins, natural chemicals that bind to the opiate receptors.

Serendipitously, that was the moment, in 1973, that scientists discovered the opiate receptor — the first neurochemical receptor in the brain.

«This study raises novel questions about the role of the opiate receptor in cancer progression,» said Ralph Weichselbaum, MD, chairman of radiation oncology and co-director of the Ludwig Center for Metastasis Research at the University of Chicago.

«Could the opiate receptor become a therapeutic target?

These findings, together with data reported several years ago on the treats» ability to turn on opiate receptors in the brain (SN: 10/12/96, p. 235), threaten to transform the image of chocolate from dietary vice to herbal medicine.

The remarkable identification of the enkephalins as the naturally occurring neurotransmitters for the opiate receptor by my friends John Hughes and Hans Kosterlitz has greatly enhanced our appreciation of how the brain perceives pain and regulates emotion.

Snyder is a recipient of the 1978 Albert Lasker Basic Medical Research Award for identifying the relation of opiate receptors to naturally - ocurring enkephalins.

The first is a protein In modern wheat that breaks down into polypeptides that bind to opiate receptors in the brain.

Gliadins, once digested, become «exorphins», which are morphine - like compounds that bind to opiate receptors in the brain.

Once Chief of Brain Chemistry in the Neuroscience Branch at the hallowed halls of the National Institutes of Health (she called it «The Palace») Candace Pert, PhD is credited with discovery of the opiate receptor.

My naturopath told me last year that milk is addictive to our brains because milk has something in it that binds to the opiate receptors in our brains, as does gluten.

«milk is addictive to our brains because milk has something in it that binds to the opiate receptors in our brains, as does gluten.

And is that working with the Opiate receptor site?

Dr. Justin Marchegiani: But the CBD, it's still hitting the Opiate receptor though, a little bit, isn't it?

Uhm — But, it's also blocking the Opiate receptors in our Immune System, in our Pituitary gland, and all [stutters] the Gluteal cells in our brain.

His theory goes that the wheat we eat today was hybridized 50 years ago, and now contains gliadin, one of two proteins that make up gluten and which binds to opiate receptors in our brains and stimulates our appetite.

It's also true that gliadin can cause our bodies to produce an opiate - like substance, gliadotropin, but our intestines don't have the type of transporter needed to absorb it, so it never reaches the brain's opiate receptors to cause that supposed appetite boost.

These morphine like compounds fit into the opiate receptor in your brain causing a similar response like heroin or vicodine.

De Meirleir explained that LDN is an opiate receptor blocker and is used in very small doses (0.5 - 5.5 mg / day) relative to its normal dosing (5 grams, which is 5000 mg).

Generally, opiate detox involves the use of Buprenorphine, an opiate agonist medication which attaches to the opiate receptors in the brain, blocking the opiates of abuse from affecting the addict.