Sentences with phrase «pharmacokinetic studies»
Pharmacokinetic studies involve examining how a drug moves through and is processed by the body. It helps us understand how quickly the drug is absorbed, distributed, metabolized, and eliminated in order to determine the right dosage and frequency for safe and effective use. Full definition
«To our knowledge, this is the first pharmacokinetic study of lithium salicylate and lithium lactate in laboratory animals,» Smith said.
sciencedaily.com
Furthermore, pharmacokinetic studies on this class of derivatives showed that an improved bioavailability was promising to further foster them for clinical use.
The single pharmacokinetic study published on non-concentrate naloxone showed that only 4 % of naloxone is absorbed when administered nasally.
However, the double positive charge at the physiological pH precludes a complete absorption, as showed by preliminary pharmacokinetic studies.
With the exception of IK14 (0.1 — 0.26 μg / mL), the values obtained (0.98 — 1.87 μg / mL) were above or consistent with expected trough values derived from our previous pharmacokinetic study [38].
Pharmacokinetic studies with sulfamethazine (500 mg) and antipyrine (15 mg / kg) were performed in 27 hypertonic patients (16 females, 11 males, 37 - 78 years) who had recovered from a
Safety of maropitant in dogs was demonstrated in a three - month oral toxicity study and a two - week pharmacokinetics study that demonstrated maropitant concentrations reached steady state after approximately four days following 2 mg / kg / day oral administration.1
UC Davis veterinary resident Lionel Sebbag, Dr. Med Vet, conducted a large pharmacokinetic study of famciclovir.
Pharmacokinetic study of oral Ɛ - Aminocaproic acid in the Northern elephant seal (Mirounga angustirostris).
individual would be 1.47 mg / kg, but our pharmacokinetic study indicated that in macaques, a dose of 5 mg / kg is to achieve MIC levels in blood for over 80 % of the treatment duration of 12 hours.
The lab also conducts bio-analytical and pharmacokinetic studies.
In a review of the «Epidemiologic Evidence concerning the Reproductive Health Effects of Caffeine Consumption: A 2000 - 2009 Update», J.D. Peck et al. scrutinized and reviewed scientific publications on the subject during this period1 A further review presented a risk analysis of in utero caffeine exposure utilizing epidemiological studies, animal and in - vitro toxicology studies and pharmacokinetic studies 2 The findings from both extensive reviews are highlighted below.
Stereoselective High - Performance Liquid Chromatography Tandem Mass Spectrometry Method for Determination of R - and S - Acenocoumarol in Human Plasma and Its Application in a Pharmacokinetics Study