Sentences with phrase «regenerative capacity»

The mechanisms controlling this high regenerative capacity are the focus of a large field of research driven by the hope to some day apply the findings to human medicine.

First: the cells demonstrate regenerative capacity by differentiating into the cell line of interest such as bone, cartilage or muscle cells.

Despite the fact that humans share many genes with these organisms, our adult regenerative capacity is limited.

When the heart muscle dies from lack of blood, it is replaced by scar tissue, since the heart has very little regenerative capacity.

Despite humans sharing many of these genes within these organisms, our adult regenerative capacity is limited.

Classically the high regenerative capacities of salamanders were considered something special and derived for salamanders.

Mice fed a calorie - restricted diet showed a greatly enhanced regenerative capacity in their intestinal tissue (right).

Drs. King and Yin commented to OTW, «The long - term goal of our research at MDI Biological Laboratory is to understand how we may be able to enhance human regenerative capacity after injury.

The study of the genetic and molecular pathways underlying regeneration in these species provides insight into the dormant molecular pathways for regeneration in humans, raising the prospect therapies can be developed to trigger human regenerative capacity.

«Mammalian heart regenerative capacity depends on severity of injury.»

«Given the remarkable regenerative capacity of limb tissues in all three model systems, we expected to identify some overlap in the molecular pathways during formation of the blastema, the critical first step in the regeneration process.

New data from the fossil record offers a new perspective on the evolution of the enormous regenerative capacities of modern salamanders.

They studied regenerative capacity in three species of sea urchins with long, intermediate and short life expectancies: the red sea urchin, Mesocentrotus franciscanus, one of the world's longest - lived organisms with a life expectancy of more than 100 years; the purple sea urchin, Strongylocentrotus purpuratus, with a life expectancy of more than 50 years; and the variegated sea urchin, Lytechinus variegatus, with a life expectancy of only four years.

«The biology we describe here suggests a new paradigm for how tissue regenerative capacity may be lost during species evolution,» says Poss.

Hammadah concludes that low leukocyte telomere length is associated with decreased regenerative capacity, independently of age and cardiovascular risk factors.

Using personalized diet, lifestyle modification, homeopathic remedies, and herbal medicine, she is able to balance and boost the body's natural regenerative capacity and help her patients overcome disease.

«It may in fact be that regeneration is ancestral, but that newts have species - specific adaptations that allow it to have such spectacular regenerative capacities compared with other vertebrates.»

A new study by researchers at Children's Hospital Los Angeles has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury.

A team of paleontologists of the Museum für Naturkunde Berlin, the State University of New York at Oswego and Brown University shows in a new study of fossil amphibians that the extraordinary regenerative capacities of modern salamanders are likely an ancient feature of four - legged vertebrates that was subsequently lost in the course of evolution.

«We were able to show salamander - like regenerative capacities in both — fossil groups that develop their limbs like the majority of modern four - legged vertebrates as well in groups with the reversed pattern of limb development seen in modern salamanders,» said Dr. Jennifer Olori of State University of New York at Oswego, co-author on the study.

When compared with control PAs, the treated scaffold showed regenerative capacity while modulating the innate inflammatory response, resulting in superior bladder function.

«The large size makes Stentor suitable to study when you want to analyse regenerative capacity at the cellular level.»

In 2017, he took up the position of Assistant Professor at the Fox Chase Cancer Center in Philadelphia, heading his own laboratory, which focuses on how tissue and organ degeneration, regeneration defects, and decline in regenerative capacity affect the initiation of cancer.

Quyyumi's team has studied circulating progenitor cells extensively, both as a biomarker predicting regenerative capacity and outcomes, and as a potential therapeutic agent.

Ed Field currently is the Chief Operating Officer of Cytomedix, Inc. (OTCBB: CMXI), a US - based company that is developing and commercializing autologous regenerative biotherapies that promote healing by harnessing the innate regenerative capacity of platelets and adult stem cells.

They tease apart the influences of age and cardiovascular disease (CVD) risk factors on these cells, whose regenerative capacity has made them the target of much investigation.

Moreover, in PrEn precursors, the Nanog low population can itself be split based on the expression of Oct4 or SSEA - 1 into a state expressing reasonably high level of PrEn genes (V+S −), and a less differentiated cell type exhibiting a PrEn bias, but with similar regenerative capacities to the Nanog high population (V+S +).

However, by combining a biomaterial with proven regenerative capacity, like collagen, with a material that can carry an electrical stimulus, it may be possible to transmit electrical signals across damaged tissue, resulting in functional restoration of the affected area.

Based on the equivalent regenerative capacity of V+S + and V − S + cells, the small number of significant gene expression changes, and the identical morphology, we assume that these two cell states have not drifted significantly apart.

When telomeres are altered adult stem cells have a maimed regenerative capacity.

Nematostella has both extreme regenerative capacities and highly manipulable development, and we will capitalise on this rare combination of traits to identify the mechanisms that restore epithelial tentacle tubes after amputation.

-- Mice have been developed with unusual regenerative capacities.

The cells have poor regenerative capacity when damaged.

If the earth's natural systems are like an endowment, then its annual regenerative capacity is like interest earned — the amount that can be spent each year without depleting the principal.

Total biocapacity can exceed the harvest Footprint even though the exploitation of various fish stocks or forest ecosystems exceeds local regenerative capacity.

Its maximum power output will be 200kW equating to 270 horsepower and the vehicle will have a max regenerative capacity of 150kW, powered by the brakes as drivers enter corners and chicanes.

Furthermore, we demonstrated cell - fusion mediated reprogramming as an efficient therapy for Parkinson's disease, and as mechanism to control liver regeneration, an organ with high regenerative capacity in mammals (Altarche - Xifro et al eBiomedicine 2016; Pedone et al..

In contrast, the adult mammalian cardiovascular system has limited regenerative capacity.

However, two weeks after injury they found that the oligodendrocyte population was largely re-established, showing the remarkable regenerative capacity of the adult zebrafish spinal cord.

The small intestinal mucosa has enormous regenerative capacity in both health and disease.

This valuable information could help scientists begin to explain why humans are less able to regenerate tissue and could also be used to improve the body's tissue regenerative capacity.

Recently, the zebrafish has emerged as a powerful vertebrate genetic model organism for studies in organ regeneration due to ease of genetic manipulation and enhanced regenerative capacity.

It encourages the removal of forests and vegetation, which promotes erosion of soil and demotes the regenerative capacity of the planet.

Frogs, meanwhile, can regenerate their tails as tadpoles, but they lose all their regenerative capacity after metamorphosis.