Sentences with phrase «regional lymph nodes»

The drug is approved to treat the tumors with or without regional lymph node involvement.

The prognosis for patients with metastatic melanoma remains poor, with 5 - year survival rates of 63 percent in patients who have metastatic disease in regional lymph nodes, and only 17 percent in patients who have metastatic disease in distant sites.

The degree of involvement of regional lymph nodes is predictive of overall survival and is also a key factor in determining the appropriateness of adjuvant therapy and the patient's eligibility for investigational trials.

Approximately 10 % of cases have metastasized to regional lymph nodes at the time a diagnosis of canine nasal carcinoma is made.

In the case of high risk features such as regional lymph node involvement, then adjuvant interferon alpha may be considered [53].

The authors found that somatic mutations of TP53 (often referred to as the master molecule) in the stroma correlate with regional lymph node metastases (spread of cancer to the lymph glands).

They also found that genetic alterations in 5 specific chromosomal spots, even in the absence of TP53 mutations, also correlate with regional lymph node metastases.

Prescription - only PALLADIA is an oral therapy indicated to treat Patnaik grade II or III recurrent cutaneous mast cell tumors with or without regional lymph node involvement.

Additional imaging with high - detail dental radiographs or advanced imaging (CT - scan) may be warranted and will aid in surgical planning as well as evaluation of other regional lymph nodes (e.g. retropharyngeal).

Lymphoma is categorized into five stages, depending on the extent of the disease in the body: single lymph node enlargement (stage I), regional lymph node enlargement (stage II), generalized lymph node enlargement (stage III), liver and / or spleen involvement (stage IV), and bone marrow and blood involvement (stage V).

At this point, your pet will undergo «staging» to determine if the cancer has spread to other areas, such as regional lymph nodes, distant lymph nodes or internal organs, such as the liver or spleen.

Ultrasonography determines the size of regional lymph nodes and the echogenecity (the characteristic ability of an organ or tissues to reflect ultrasound waves and produce echoes) of other abdominal organs especially liver and spleen.

After eight months of ADT, all patients received 46 Gy2 of external beam radiotherapy to the prostate and regional lymph nodes.

Radiotherapy to the chest wall and regional lymph nodes (under the arm, above the collar bone and under the breast bone), known as regional nodal irradiation, is used after mastectomy in women with node - positive breast cancer who are treated with adjuvant systemic therapy.

The researchers took multiple samples from primary tumors, regional lymph nodes and distant metastases.

Researchers wanted to determine if ipilimumab could improve the survival of advanced - stage melanoma patients if it was given after the surgical removal of both their primary melanoma tumors and their regional lymph nodes.

They discovered that patients who had microscopic metastatic disease in their regional lymph nodes and a tumor that had a breakdown of the overlaying skin responded best to ipilimumab treatment.

Inhibition of SDF - 1 / CXCR4 interaction using an anti-CXCR4 monoclonal antibody significantly impairs the migration of breast cancer cells to regional lymph nodes and lung in nude mice [28].

Instead, immune responses are induced in the local and regional lymph nodes (ie, the tonsils, adenoids, and cervical lymph nodes).

Antigens flood into the submucosa; from there they migrate into the regional lymph nodes and then into the circulation.

Numerous substances (electrolytes, proteins, hormones, toxins, debris) and immuno - competent cells (lymphocytes, macrophages) pass through the regional lymph nodes, where this fluid is filtered, purified and concentrated.

While this could have been diagnosed on ocular ultrasound, CT allowed us to also image the regional lymph nodes and thorax (unremarkable, within normal limits).

It spreads deep into adjacent tissues and can metastasize (spread) to the lungs, regional lymph nodes, and the skin.

After unsuccessful attempts to excise the infected tissue and to treat the condition with sodium iodide, the infection spread to the regional lymph nodes, liver, and kidneys.

When metastasis occurs, spread is typically to the lungs or regional lymph nodes.

Spread of mammary carcinomas in both dogs and cats is primarily to regional lymph nodes and lungs.

AGA can go to any tissue in the body, but tends to spread first to the regional lymph nodes (primarily sublumbar nodes).

The most common sites of metastasis are regional lymph nodes (60 - 80 %) and lungs (50 - 60 %), and metastasis at the time of diagnosis is associated with a poorer overall prognosis.

Occasionally, metastasis can occur at distant sites (lungs, liver) without evidence of spread to the regional lymph nodes (termed «skip metastasis).

They are typically red, proliferative growths that can potentially metastasize to the regional lymph node.

Sometimes, cancer cells from other tissues may travel through the lymph and collect in the regional lymph nodes (lymph nodes that drain a specific area or region of the body) where they continue to multiply.

Although rare, it can metastasize to the regional lymph nodes and lungs, so a fine needle aspirate of the lymph node and chest X-rays are recommended.

Malignancies are locally infiltrative and metastasis to regional lymph nodes is common.

Ultrasonorgraphy is important in viewing the regional lymph nodes and metastases in other abdominal organs.

The most common sites of spread are regional lymph nodes and the lungs.

Malignant melanomas are characterized by rapid growth, local invasiveness, and early metastasis to regional lymph nodes and lungs.

Urinary systems: kidneys, urinary bladder, regional lymph nodes 3.

These tumors are more aggressive than gingival SCC because they are locally invasive AND nearly all have metastasized to the regional lymph nodes at the time of presentation.

Inflammatory carcinomas aggravate with a lightening speed and metastasize to regional lymph nodes and lungs.

But the malignant ones tend to be locally aggressive and have a high potential to spread to the regional lymph nodes and lungs.

This tumor is typically more aggressive, more likely to invade into underlying bone and to metastasize to regional lymph nodes and lungs than the more common digital SCC.

As a result of the metastasis to regional lymph nodes, it is recommended that sublumbar be irradiated.

Anal gland tumors are almost always malignant and may already have spread to regional lymph nodes and then to various internal organs by the time of the initial diagnosis.

If the mammary tumor is malignant, the surgical site and regional lymph nodes should be checked for local tumor recurrence and metastasis, respectively, every 3 months for the first 12 months after surgery and then every 6 months thereafter.

Approximately 10 % of dogs will have metastasis to regional lymph nodes and approximately 3 - 36 % will have spread to the lungs so continued monitoring with chest x-rays every 2 - 3 months is warranted.

Aspiration of regional lymph nodes — especially the mandibular lymph nodes — may reveal the presence and spread of primary nasal adenocarcinoma.

Transitional Cell Carcinomas tend to be fairly aggressive, spreading to regional lymph nodes and other organs in the body.

They also spread (metastasize) to the pleura (covering) of the lung and to regional lymph nodes.

The regional lymph nodes (glands) are often examined, because if the cancer has spread to the nodes at the time of surgery, a successful outcome is less likely.

At the time of surgery, it is recommended to remove the regional lymph node and submit separately for histopathology assessment to rule out lymph node metastasis.