Sentences with phrase «regulatory switches»

Only in recent years has science determined that developmental regulation proceeds through a sequential activation of series of regulatory switches that, in turn, activate networks of other genes.

What makes a horse different from a tiger, a mouse and a walrus is the set of regulatory switches in the DNA that dictate where, when and for how long those genes are active.

The researchers discovered that hundreds of gene regulatory switches known as enhancers are used differently in the two species.

But the discovery last year that patches of junk DNA are identical in humans, mice, and rats indicated that the regions might contain important regulatory switches that control basic biochemistry and development, which might help organisms build sophisticated bodies.

Remains of the transposons that infected humans have been recycled into more than a thousand regulatory switches found only in humans, he discovered.

The team found that Notch uses different regulatory switches in the genome, called enhancers, in different cell types.

«If you turn back on an immune regulatory switch that the body has decided to turn off,» Walker cautions, «you could trigger serious immunological problems.»

A widespread family of serine / threonine protein phosphatases shares a common regulatory switch with proteasomal proteases Bradshaw, N., et al., eLife doi: 10.7554 / eLife.26111.

This confirmed that the gene regulatory switch is highly specific to one cell type, monocytes and that tumor cell invasion in the absence of this population had nothing to do with deregulated macrophage activity.

miRNAs function as important regulatory switches, influencing cell fate decisions and tumor development.

Developmental regulation proceeds through the sequential activation of a series of regulatory switches that in turn activate networks of other genes.

«The complexity of our biology resides not in the number of our genes but in the regulatory switches,» Eric Green, director of the National Human Genome Research Institute and collaborator on the ENCODE project, said in a press briefing September 5.

But a research team led by Mark Zylka, PhD, associate professor of cell biology and physiology, found that an autism - linked mutation destroys this regulatory switch.