Sentences with phrase «sequence differences»

In many cases, the investigators found that some DNA sequence differences linked to diseases in humans appeared to have counterparts in the mouse genome.

NYGC computational biologists and members of the Simon Laboratory at The Rockefeller University discussed the possibility of using a series of computer algorithms to search for sequence differences between the tumor samples and samples of healthy liver tissue.

Using these data, the team built a diagnostic model that predicts who is likely to experience these problems based on sequence differences in a gene coding for an immune protein called interleukin - 4 as well as variations in serum concentrations of three other immune proteins.

Following re-design of the R5 - ZFNs to account for sequence differences between the human and macaque alleles, we found that ZFNs could disrupt both alleles with reasonable efficiency in macaque CD4 + T cells.

Zoghbi's lab meticulously analyzed each gene in this region, systematically eliminating genes based on sequence differences between healthy controls and Rett syndrome patients.

The study, led by Dr Chris Tyler - Smith of the Wellcome Trust Sanger Institute, analysed sequence differences between the Y chromosomes of more than 1200 men from 26 populations around the world using data generated by the 1000 Genomes Project.

Egli suspects that the resurgence happened because one mitochondrion was able to copy its DNA faster than the others could, which he says is more likely to occur when large DNA - sequence differences exist between the two populations of mitochondria.

As molecular genetic testing and electronic healthcare records become increasingly common features of modern medical practice, there is a need to integrate information in genetic databases to establish a detailed understanding of how genome sequence differences impact on human health.

When you are looking for potential SNPs, particularly without a reference genome, you run the risk of identifying sequence differences between duplicated sequences rather than differences between individuals.

These proteins display large sequence differences between themselves (Supplementary Table 1) and they are properly folded, highly stable, active and share the β - lactamase fold11.

By comparing almost 30 million DNA sequence differences in more than 173,000 people with variation in the physical properties of blood cells the scientists identified 2,500 previously undiscovered locations in the genome that influence blood cell characteristics and functions.

DNA sequence differences between the pectate lyase genes from the cultivated tomato and S. pennellii can then be used as markers to screen the progeny from this cross.

They then looked for sequence differences in three mitochondrial genes and 10 microsatellites, short bits of repetitive DNA sequence that lengthen and mutate through time and thus indicate the relatedness of organisms.

Even if we document all of the perhaps 40 million sequence differences between humans and chimps, what do they mean?

«The sequence difference is larger than the average sequence difference between humans and chimps, so we estimate it occurred at least 4 million years ago,» Andersson explained.

The sequence difference between the chromosome variants is as large as 1.4 percent that is higher than the average sequence difference between human and chimpanzee chromosomes!

Sequence differences in the internal transcribed spacers of DNA among four species of hookworm.