Sentences with phrase «several genes»

The results are consistent with other biological studies which point to the likely interaction of several genes in producing complex disorders such as autism [36] and schizophrenia [37].

It also gives the possibility to target multiple genes in one experiment and thereby to relatively easy investigate the combined effect of several genes in a particular context.

While those studies identified several gene variants that appeared to increase the risk of each disorder, none of the associations were strong enough to meet the strict standards of genome - wide significance.

They hit pay dirt on chromosome 10, finding such a marker in a region with several genes thought to affect heart function.

The study found several genes that are associated with resistance to antibiotics, including new genes that might point to previously unknown mechanisms of drug resistance.

The segment contains several genes, one of which raises the risk of autism.

Scientists have uncovered several gene mutations that sharply increase the chances of developing autism.

Along the way, researchers have turned up several genes related to longevity.

First, the researchers found that the activity of several genes responsible for recognizing and repairing damaged DNA is turned down during the course of the infection.

The mode is in fact likely to be complex, involving several genes [similar to an attribute that can be measured on a scale like height].

The analysis identifies several genes that are associated with wool production.

Several genes in the brain appear to help the flies learn to distinguish between normal - calorie and high - calorie foods — and to remember to choose the healthier option later.

Currently, the researchers are studying the function of several genes with human - specific expression patterns.

Recent research has uncovered several genes that can elevate the risk of developing AD.

«We already know several genes involved in balding and hair color but this is the first time a gene for greying has been identified in humans, as well as other genes influencing hair shape and density,» said lead author, Dr Kaustubh Adhikari, UCL Cell & Developmental Biology.

Snake venoms are complex protein mixtures encoded by several gene families and these proteins function synergistically to cause rapid paralysis or death in prey.

That included several genes linked to novelty - seeking in vertebrates, such as receptors for the neurotransmitters dopamine and glutamate.

But over the next five years she isolated one gene, then another, and another, until more than 50 mutations on several genes associated with epidermolysis bullosa had been nailed.

Although the study of psychological genetics is in its infancy and much is still to be learned, in this article, we present data suggesting that variation in several genes known to affect brain function appear to influence the degree to which one is emotionally responsive to the social environment.

Ataxin - 7 is one of several genes associated with neurodegenerative diseases, including Huntington's disease and other spinocerebellar ataxias.

In 2013, CRISPR passed two important tests: It works in human cells, and it can target several genes at once.

They identified five missense, one non-sense, three frameshift mutations and two large deletions involving several genes including RUNX1.

The DNA from several genes of the bat parasites was sequenced at the Museum's Sackler Institute for Comparative Genomics, resulting in the most comprehensive evolutionary tree of life for malaria parasites of bats to date.

If the beetle does evolve to resist an RNA molecule, he says, geneticists could easily launch a new assault: just «slide the sequence over» by a few letters or target several genes at once.

Moreover, recent data also show that in response to brain damage caused by aging, amyloid deposition, demyelination, and other insults, microglial cells activate several genes, including APOE, in order to more efficiently scavenge and clear tissue debris that are very rich in cholesterol due to the natural composition of the brain, which is mostly made of fats.

This usually requires adding several genes encoding the enzymes that catalyze each step of the overall synthesis.

The Physiology or Medicine Prize recognized work on how several genes work together to control the basic circadian clock, encoding proteins that build up during the night and are broken down during the day.

Master regulators control several genes and processes in metabolic or regulatory pathways.

One of the key caveats at the time, however, was that the technique required the use of a virus to introduce several genes into the skin (or other) cell, and these would remain in the cell, and so might contaminate the resulting stem cell or create cancer risks.

Genes also play a role in menopause, and two research teams have identified several gene variants associated with advancing or delaying menopause by as much as two years.

Genome comparison revealed that the great expansion of several gene families in the deep - sea mussel may be related to its adaptation to the deep sea.

The researchers found that miRNA - 34a regulated several genes that encode components of the Notch pathway.

New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several genes that can be associated with health problems for smokers, such as increased risk for cancer and diabetes.

«Not only did the study reveal several genes linked to pre-term birth, it also identified a simple, low - cost solution — selenium supplements for expectant mothers — that, if confirmed, could save thousands of lives.

The researchers found that the salamanders overexpress several genes that might suppress an immune response, suggesting that the host cell experience is neutral or beneficial.

Jeffrey Hall and Michael Rosbash of Brandeis University in Waltham, Massachusetts, and Michael Young of The Rockefeller University in New York City share the prize equally for their work on how several genes work together to control the basic circadian clock, encoding proteins that build up during the night and are broken down during the day.

Although there are currently no FDA - approved gene therapies in the United States, it is anticipated that within the next few years several gene therapies will be approved, including for some forms of blindness.

The combination of the University of Utah's genomics expertise and local families» detailed genealogical data has been key to discovering several genes responsible for certain forms of breast and colon cancer.

«The greatest hope for achieving durable resistance to rust diseases is to make wheat's resistance genetically complex, combining several genes and resistance mechanisms,» Singh explained.

Several genes influence a person's likelihood of developing fatty liver disease, but a recent study in Nature Genetics found that people with high - risk gene variants were much more likely to actually get the disease if they were obese than if they were normal weight.

RNA sequencing of both single and clustered CTCs from breast cancer patients identified several genes expressed at elevated levels in CTC clusters, one of which — a protein called plakoglobin — also was overexpressed in the primary tumors of patients with reduced survival.

Through the systematic analysis of ommochrome and porphyrin biosynthetic pathways, the authors identified several genes required for producing planarian pigment.

Several genes also influence a threshold trait, but the trait will not be expressed unless a critical number of those genes is present1, 2.

Over the past decade, several dozen genes have been identified as potential culprits, and scientists believe that several genes cause disruptions in protein formations predisposing a person to schizophrenia.

In 2016, the Washington Post reported that scientists have found several gene changes that have taken place since the Paleolithic Era in response to man's adoption of agriculture:

To transiently silence in parallel several genes, we take advantage of «home designed» or commercially defined sets of siRNA that we transfect in one mesodermal progeny derived from DM1 - PGD - hES cells in 96 - or 384 - well plates by the use of the Bravo automate from Velocity 11.

In order to make a glowing plant, they needed to insert several genes normally found in bioluminescent bacteria into their Arabidopsis plant's genome.

The cannabinoids inhibited the expression of several genes critical to angiogenesis known as the VEGF (vascular endothelial growth factor) pathway.

Over the last 6 million years, those accumulated mutations have inactivated several genes.