Sentences with phrase «simian immunodeficiency»

Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys.

In April two studies of simian immunodeficiency virus, a kin of HIV that infects monkeys, reported that the virus swiftly infects and decimates key immune cells in the gut within days, not years, of infection.

Monkey viruses have contaminated vaccines in the past, and several species, such as African green monkeys, are commonly found to be infected with simian immunodeficiency virus (SIV), a relative of HIV.

And in a study of monkeys, researchers discovered that a cytomegalovirus - based vaccine protected 50 percent of animals from infection by simian immunodeficiency virus.

Taking a cue from AIDS researchers, who use simian immunodeficiency virus in monkeys as a model for HIV infection, Fred Wang of Brigham and Women's Hospital and Harvard Medical School in Boston set out to find a primate version of EBV.

Both arose from simian immunodeficiency viruses (SIVs) of other primates.

The common chimpanzee, for example, shows selection for a version of a gene that may be involved in fighting retroviruses, such as HIV — a genetic variant not found in humans or bonobos, which may explain why chimps get a milder strain of HIV (called simian immunodeficiency virus) than humans do.

Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin - 1 beta (IL - 1β).

It's called SIV, which stands for simian immunodeficiency virus.

Researchers for the past decade have focused on the T cell approach, based on studies showing that monkeys receiving such vaccines against simian immunodeficiency virus, related to HIV, lived longer or had lower viral levels than usual.

Now a research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) in collaboration with the U.S. Military HIV Research Program has demonstrated that the viral reservoir is established strikingly early after intrarectal simian immunodeficiency virus (SIV) infection of rhesus monkeys and before detectable viremia.

Infection researchers from the German Primate Center (DPZ)-- Leibniz Institute for Primate Research have in cooperation with international colleagues tested a new vaccination strategy against the HIV - related simian immunodeficiency virus (SIV) in rhesus monkeys.

Magnitude and quality of cytokine and chemokine storm during acute infection distinguish non-pathogenic and pathogenic simian immunodeficiency virus infections of nonhuman primates.

Magnitude and quality of cytokine and chemokine storm during acute infection distinguish non-progressive simian immunodeficiency virus infections of nonhuman primates.

Given that adipose tissue (which makes up between 15 and 20 % of the body weight in healthy people) is a source of inflammation in obese individuals, Christine Bourgeois and Olivier Lambotte, from the University Paris SUD, France, and colleagues, decided to investigate a possible role of the adipose tissue in humans infected with HIV and in macaques infected with simian immunodeficiency virus (SIV, an HIV relative that causes AIDS - like disease in some non-human primates).

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number of dormant «viral reservoirs» that pose a risk of reactivation.

2012 — Novel Ad26MVA vaccine provides protection against SIV — Results found Ad26 / MVA vaccine combinations can provide partial protection against infection by Simian Immunodeficiency Virus (SIV) in rhesus monkeys.

Watkins and colleagues reported last year that rhesus monkeys injected with four genes from simian immunodeficiency virus — the ape version of HIV — had low levels of virus in their blood up to a year after infection but did not develop full - blown AIDS.

The 1996 study showed that female rhesus macaques with progesterone implants were 7.7 times more likely to be infected with simian immunodeficiency virus than macaques that had a placebo implant.

So far only one person, a 62 - year - old Cameroonian woman living in Paris, France, has been found to be infected with the virus, which closely resembles strains of simian immunodeficiency virus (SIV) recently discovered in wild western gorillas.

To study the pathogenesis of HIV - induced PNS disease, Jamie Dorsey, Research Technologist, and the research team led by Dr. Mankowski developed a simian immunodeficiency virus (SIV)- infected macaque model that closely reflects key peripheral nervous system (PNS) alterations seen in HIV patients with peripheral neuropathy.

Their hypothesis draws on the observation that sooty mangabeys (monkeys) infected with the simian immunodeficiency virus (SIV)-- a pathogen thought to be the ancestor of HIV — have a high viral load but low immune activation.

But while HIV - 2 is very like some of the simian immunodeficiency viruses, HIV - 1 is quite different from most of them, and it is HIV - 1 that is found in Zaire and Rwanda.

Vaccine - mediated protection of nonhuman primates against low doses of cell - free HIV - 1, HIV - 2, or simian immunodeficiency virus (SIV) has been demonstrated.

These features of the immune response in healthy HIV - infected children show a striking resemblance to that observed in the more than 40 species of African monkeys which are the natural hosts of Simian Immunodeficiency Virus (SIV)-- from which HIV itself is derived.

Separation of the island of Bioko from West Africa about 10,000 years ago dates the origins of simian immunodeficiency virus.

HIV's close cousin, the simian immunodeficiency virus (SIV), has been around for tens of thousands of years — much longer than the few hundred years that some studies had suggested.

Simian immunodeficiency virus (SIV) lineages have been identified that are endemic to Bioko Island.

Researchers believe that sometime in the 1930s a form of simian immunodeficiency virus (SIV) jumped to humans who butchered or ate chimpanzee bush meat in the Democratic Republic of Congo.

Similarities with the simian immunodeficiency virus (SIV) that infects chimpanzees in west - central Africa suggest the original source of the infection, which probably spread to people who hunted and ate the apes.

The ebola virus is responsible for thousands of gorilla and chimpanzee deaths in Africa and the origin of HIV, the virus which causes AIDs, is SIV, simian immunodeficiency virus.

One, the simian immunodeficiency virus, is the predecessor of HIV; the other is simian T - lymphotropic virus 1, whose descendant in humans, HTLV - 1, can cause leukemia.

The sooty mangabey, found in West Africa, has somehow adapted to the simian immunodeficiency virus — the nonhuman version of HIV — so that even with a high viral load, it rarely gets sick.

A new study led by scientists at Beth Israel Deaconess Medical Center (BIDMC) shows that an HIV - 1 vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.

The virus most closely related to HIV - 1 is a simian immunodeficiency virus (SIV) thus far identified only in captive members of the chimpanzee subspecies Pan troglodytes troglodytes.

These teams earlier had found persuasive evidence that chimps harbor a simian immunodeficiency virus called SIVcpz that became HIV - 1 — the predominant cause of AIDS in humans (ScienceNOW, 1 February 1999,)-- but they had discovered precious few infected animals to make the case.

The tale of the «cut hunter» is just a theory, but it's considered one of the most plausible scenarios for how a simian immunodeficiency virus jumped from chimps to humans and became HIV.

Because of HIV's close resemblance to a simian immunodeficiency virus, researchers knew it must have originated as a virus carried by chimps.

SIV -(simian immunodeficiency virus): an HIV - like virus that infects and causes an AIDS - like disease in some species of monkeys.

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number Read more about Gene - editing and vaccines could improve HIV treatment - Scimex

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus - based lentiviral vector system.

Reporting in Nature Medicine this week, Philip Johnson, a professor of pediatrics at the University of Pennsylvania, in Philadelphia, and his colleagues managed to protect monkeys from infection with the simian immunodeficiency virus (SIV), the animal model that is closest to HIV, by shuttling a gene into their muscles that produces antibody - like molecules that work against SIV.

Results from a recent study show that novel vaccine combinations can provide partial protection against infection by Simian Immunodeficiency Virus (SIV) in rhesus monkeys.

Results from a recent study published in Nature show that novel vaccine combinations can provide partial protection against infection by Simian Immunodeficiency Virus (SIV) in rhesus monkeys.

The research showed evidence that in rhesus macaques infected with simian immunodeficiency virus (SIV), the monkey form of HIV, loss of IL - 17 producing CD4 + and CD8 + T cells was associated with damage to the colon epithelium and with immune activation (see Monkey Matters, IAVI Report, Nov. - Dec.