Four proteins that can transform adult cells into embryonic - like ones can also turn back the aging clock, a
new study in mice suggests.
The mystery chemical messenger, a new
study in mice shows, is one usually associated with mood — serotonin.
A recent
study in mice found just a single session of exercise before catching flu reduced disease severity, although regular exercise beforehand worked even better.
And while humans missed out on these abilities in the evolutionary lottery, a
recent study in mice shows we're making small progress to achieving this dream.
When the researchers did similar
studies in mice with viral infections, they found the opposite effect.
A new
study in mice reveals that a body chemical related to a compound in marijuana may complicate pregnancy if present in excessive amounts.
Researchers don't have one in hand yet, but they have a clear idea of what it should look like, based
on studies in mice.
Depending on results from further
behavioural studies in mice and humans, the abnormalities could then be treated in parallel with seizures.
Now, a new
study in mice hints at another reason why breast - feeding the second baby could be easier: Our bodies seem to remember how to make milk.
The research is in the very early stages, but the researchers have so far shown promising results in a proof of
concept study in mice.
Various studies in mice have shown that weight loss is aided by the conversion of cells — specifically white fat cells to brown cells.
But the severity of the illness may depend on what time — day or night — the infection took place, a new
study in mice finds.
A
new study in mice suggests that the desire for calories in sugar is stronger than the drive for sweetness.
3/29/2007 UCSD Researchers Identify Critical Receptor in Liver Regeneration In
studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that A hepatic stellate cell activated by the p75 Neurotrophin Receptor promotes repair in the livera cellular recept... More...
Lifelong Intestine Memory
In studies in mice, the researchers show that the mucosal immune system can lead to a lifelong memory in the intestines of mice.
A preclinical
study in mice published by Cell Press January 16th in the journal Cell reveals that drugs known as histone deacetylase inhibitors (HDACis) can enhance the brain's ability to permanently replace old traumatic memories with new memories, opening promising avenues for the treatment of posttraumatic stress disorder (PTSD) and other anxiety disorders.
Results of
previous studies in mice of bexarotene's effect on AD have been mixed, and none of those studies were done in mice that carry a human APOE gene and also develop progressive, AD - like pathology.
Their findings
from studies in mice, published online in the journal Neuron on June 20, 2013, provide a molecular target for developing drugs to prevent the onset of epilepsy, not just manage the disease's symptoms.
A trio
of studies in mice are revealing that the thalamus sustains the ability to distinguish categories and hold thoughts in mind.
Genetic
studies in mice point to a protein called POU6F2, which can modulate corneal thickness, as a possible risk factor for glaucoma in humans, report Eldon Geisert of Emory University, and colleagues, January 25th in PLOS Genetics.
Because the compound is metabolized too rapidly
for study in mice, the team mimicked its effects by knocking out cytochrome B in C. albicans and infecting mice with this mutant strain.
Because genes and the proteins they code for are often highly conserved across species, the researchers suspect their discoveries — boosted by
preliminary studies in mice — could lead to new treatments for people whose insomnia or off - hours work schedules keep them awake long after their heads hit the pillow.
Preclinical studies in mice and human cells suggested that the removal of SnCs significantly reduced the development of post-traumatic OA and related pain and created a prochondrogenic environment for new cartilage to grow and repair joints.
A new Duke
University study in mice suggests that in Alzheimer's disease, certain immune cells that normally protect the brain begin to abnormally consume an important nutrient: arginine.
The new
study in mice also shows that repeated mild concussions with only a day to recover between injuries leads to mounting damage and brain inflammation that remains evident a year after injury.
Studies in mice indicated that drugs that activate the surface protein TRPA1 on pain - sensing nerve cells intensify postoperative pain.
A new University of
Iowa study in mice shows that drug - induced changes to the gut microbiome can cause obesity by reducing the resting metabolic rate — the calories burned while sleeping or resting.
A new Duke University
study in mice links three previous and, until now, apparently unrelated hypotheses about the causes of schizophrenia, a debilitating mental disorder appearing in late adolescence that affects how people think, act and perceive reality.
Dr. Sawyer's more recent work in prostate cancer has defined critical signaling pathways for disease initiation and progression
through studies in mouse models and human tissues.
Taking advantage of fly genetics The research will combine the strength of the fly system (animals that are short lived but complex enough to model regenerative activity in vertebrates) with
genetic studies in mice to understand the role of mTOR signaling in maintaining the health of adult stem cells in both species.
Using studies in both mice and humans, they found that exposure to farm dust increases expression of a protective protein that suppresses the inflammatory immune system by modifying the communication between the lining of the lungs and the immune system.
Based on
pre-clinical studies in mice and case studies in patients, it is obvious that the RKD should be investigated for its therapeutic potential for managing GBM and other malignant brain cancers.
The Institute's phenotyping platforms are adapted for the study of mutant mice and genetic reference populations but can also be used for preclinical studies including the validation of therapeutic targets as well as pharmacological and
toxicological studies in the mouse.
«Other research methods,
including studies in mice, suggested a later and more focussed role for OCT4, so our results highlight the need for human embryo research.»
A recent
study in mice compared the metabolic effects of Agave nectar and sucrose (plain sugar) after 34 days.
Women's decreased ability to produce healthy eggs as they become older may be due to excessive scarring and inflammation in their ovaries, reports a new Northwestern
Medicine study in mice.
Their in
vivo studies in mice have shown that neural stem cells can be genetically modified in the lab to secrete anticancer agents, like interleukin - 12, so that they will track down and kill cancer cells in both the tumor and its satellites without harming normal brain tissue.
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