Sentences with phrase «target organ»

In target organs, long - range signals act in concert with tissue - autonomous ones to regulate the final size of a given tissue.

The skin appears to be the primary target organ for these allergies in pets, in humans; the primary target is our respiratory system.

They are also working on nanoparticles that target organs other than the liver, which is more challenging because the liver is a natural destination for foreign material filtered out of the blood.

It's also a great target organ because it's small and enclosed.

In this review, we highlight this technological opportunity by focusing on key target organs associated with drug safety and metabolism.

Thus, repeated or prolonged exposure to the substance can produce target organs damage.

A low quality pet food company will use scraps from a rendering plant, including many things that are not digestible, rather than targeted organ meat.

First, despite the fact that the work of educators targets the organ of learning, the brain, most teachers and school leaders have little understanding of the architecture of the brain and how it receives, filters, and applies information.

We performed histological examination of GVHD target organs (liver, lung, small intestine, and colon) and the tongue, which served as a surrogate for skin damage (37), 4 wk after transplantation.

On the other hand, if you're looking for targeted organ support, you may be interested in our GRASS FED BEEF HEART to support heart health (or) our GRASS FED THYROID to support a struggling thyroid (or) our GRASS FED THYMUS to support thymus function and immune health... you get the picture.

Is it the case that the red cells would be expected to reach target organs faster than unattached drugs in the bloodstream?

Mutations in the gene of SCNN1A have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt - wasting disease resulting from target organ unresponsiveness to mineralocorticoids.

By secreting SDF - 1, lymphatic vessels guide the metastasis of CXCR4 + / CD133 + melanoma cells towards target organs [40].

Chronic GVHD has a different pathophysiology and different target organs than aGVHD.

The work, recently published in Science Magazine, reveals the details of how the malaria parasite invades its initial target organ, the liver.

Such a system is designed to reach the specific target organ in the body, is nontoxic, can be manufactured at a large scale, and has a higher ratio of medicine to the nanoparticles carrying it.

However, beyond relatively easily targeted organs, genomic therapies like this will require significant advances in methods to deliver the large biological molecules involved to the diseased tissues.»

«With the chicken embryo, we can look at a very wide range of developmental stages, and we can identify potential target organs.

By binding to vitamin D - binding protein (VDBP), a carrier protein in the plasma, calcitriol is transported to various target organs.

Familial syndrome combining deaf - mutism, stippled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone.

Based on Dr. Fasano's research, the same approach should apply to all autoimmune conditions, although triggers may be different for the particular target organ that is affected.

Distribution through the bloodstream results in infection of other target organs including kidneys, liver, spleen, CNS, & reproductive tract.

According to some sources, prolonged / repeated exposure can cause target organ damage.

A recent observational study investigating sex differences in target organ damage, in insulin - resistant patients, demonstrated increased vascular and renal damage in women, who had increased intima - media thickness progression, higher numbers of vascular plaques, and reduced pulse wave velocity compared with men (321).

The infiltration of Th1 and Th17 cells into GVHD target organs (liver and lung), as well as the serum level of related cytokines, also were increased in allogeneic BMT recipients.

On the other hand, if you're looking for targeted organ support, you may be interested in our GRASS FED BEEF HEART to support heart health (or) our GRASS FED THYROID to support thyroid health... you get the picture.

Their South Korean counterparts are modeling how drugs reach target organs, developing new approaches to analyzing big data sets, and delving into the complex geometry of computer animation.

Tissues being sampled include biopsy material from target organs, peripheral blood cells and serum / plasma, germline DNA, and stool for microbiota analysis.

Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD - DIABETES study

As a result, they survive to cross the gastrointestinal lining, enter the bloodstream, and go to target organs, causing allergic reactions throughout the body.

Nerve cells (or neurons) in the periphery, i.e. the outskirts of the body, as opposed to the central nervous system or CNS), are highly asymmetric: they have a cell body from which a long protrusion called an axon extends to another nerve cell or a target organ like muscle, along a specific transmission route.

The system can be adapted to target any organ, and the process takes about 14 seconds per fish.

In rheumatoid arthritis, we've never gone to the target organ.»

«They provide unique, biocompatible platforms for wireless delivery of light to virtually any targeted organ in the body,» he said.

With millions of possible combinations, identifying the optimal nanoparticles to target each organ has been overwhelming.

Contrast agents that exert a strong effect are said to have high «relaxivity,» which enhances the visual contrast between the target organ and surrounding tissue.

To induce cancer mutations, the investigators package the genes for Cas9 and the RNA guide strand into viruses called lentiviruses, which are then injected into the target organs of adult mice.

All the data are processed by computer to produce a series of image slices representing a three - dimensional view of the target organ or body region.

Researchers will now study how these different types of messengers develop, exactly what molecules each of them carry, and what their functions are at their target organ sites.

To deliver the genes for Cas9 and the RNA guide strand, the MIT team packaged them into viruses called lentiviruses, which can be injected into the target organs of adult mice.

Circulating tumor cells then exploit endothelial cell receptors in distal vascular beds to promote their arrest and retention in target organs (7).