The phrase
"to inherit the disease" means getting a disease from your parents or family members because it is passed down through their genes.
Full definition
At this time, the best way to improve the odds of healthy puppies is to screen all breeding stock
for inherited diseases where testing is possible.
That's a disadvantage when it comes to
treating inherited diseases, but it means that diseases like cancer can be treated with less risk of side effects.
There is not much that we can do about genetic transmission in randomly bred animals, but for purposely bred animals, breeders must use due diligence to
prevent inherited disease.
Closed register breeding is very effect for retaining good qualities in some of our favorite breeds, but unfortunately it also makes them more susceptible to
many inherited diseases.
Although there are no guarantees, the probability that a dog will
develop inherited disease is reduced when animals in its pedigree have tested normal.
It is worth asking why so much progress has been made in
canine inherited diseases and so little in the genetics of canine behaviours.
In terms of genetics, dogs are very similar within, but diverse across breeds, and so they offer a unique possibility to study genetic factors
driving inherited diseases.
Ensure your puppy is from a reputable source with both parents being fully screened before breeding and that the results
confirmed inherited diseases were not a problem.
When you find yourself under fire it may seem there's no point in trying, but the attitude
toward inherited disease is shifting.
So the risk is your puppy has a higher chance
of inherited disease and behavior problems than the general population.
In the next few years, your active participation will be crucial in making possible the research that can result in effective diagnostic tests
for inherited diseases.
The big question is «How can we promote the development and use of molecular genetic tests for more
inherited diseases in more breeds»?
According to the Huntington's Society of America, about 30,000 people in the United States have Huntington's symptoms and 200,000 people are at risk of
inheriting the disease from a parent.
In addition to his other roles at the institute, he is director of the Clinical Molecular Genetics Training Program, an executive faculty member of the Joint National Institutes of Health - Johns Hopkins University Genetic Counseling Training Program, and the project officer for the Center for
Inherited Disease Research in Baltimore, a research center that analyzes common disorders caused by the actions of multiple genes and interactions with the environment.
Familial Shar Pei Fever is a serious and
common inherited disease causing chronic fevers, swollen hocks and debilitation.
But once these time - ticking bombs explode, you end up with stillbirths at every litter, adult dogs
with inherited diseases, and you have to start all over again.
Huntington's Disease (HD) is an autosomal dominant
inherited disease characterized by an abnormal and unstable expansion in the number of CAG trinucleotide repeats in exon 1 of the huntingtin gene (Group HsDCR, 1993).
Geneticists have so far concentrated on genes that are linked to disease: first the simple but
rare inherited diseases like cystic fibrosis (the gene for which is on chromosome 7) or Huntington's (chromosome 4), then the environmental diseases for which different people inherit different susceptibilities, such as Alzheimer's (chromosome 19) or breast cancer (chromosomes 13 and 17).
Most mutations are neutral, having no effect on gene function; others are harmful, such as the ones that cause
inherited diseases like cystic fibrosis.
OPTIGEN is a service company established to provide DNA based diagnoses and information
about inherited diseases of dogs.
Stem cells may be used in conjunction with gene therapy to correct
inherited diseases such as thalassemia [a blood disease that causes anemia]-- it would be wonderful to be able to apply a single treatment fairly early on in a child's life and have it be fully effective from then on.
The requirements for a CHIC number have been tailored to meet the needs for Swedish Vallhunds based
on inherited diseases that are of the greatest concern and for which some screening test is available.
Many sires, both affected and unaffected, produce far more offspring than the recommended limit of 105 puppies, which makes it quite difficult to measure the effect of preventive actions, and to
control inherited diseases, such as distichiasis, within a population.
The
recessively inherited disease inexorably destroys the motor neurons of the spinal cord and brain stem, hobbling muscle movement, including breathing.
For the first time in the United States, scientists have edited the genes of human embryos, a controversial step toward someday helping babies
avoid inherited diseases.
An inherited form of kidney disease affects English Cocker Spaniels, while Dalmatians are prone to kidney stones and Basenjis suffer from Fanconi Syndrome, a potentially
fatal inherited disease in which the kidneys fail to reabsorb nutrients.
The study is a «real landmark» because so little has been known about LCA, the
only inherited disease of the retina that strikes early in childhood, says Samuel Jacobson, an ophthalmologist at the University of Pennsylvania's Sheie Eye Institute.
People with the rare
inherited disease also have frequent nosebleeds, as many as seven a day, that can become so severe that patients require skin grafts in their noses or even more desperate measures to lead normal lives.
For several years, the couple will be helping to establish both a mouse genetics facility at inStem and a lab that will
study inherited diseases of the heart muscle called cardiomyopathies.
Mark Kittleson, DVM, PhD, DACVIM, and his colleagues at the University of California, Davis, determined that HCM is an autosomal
dominant inherited disease in Maine Coon Cats, and established guidelines for diagnosis of HCM using ultrasound imaging of the heart.
Phrases with «to inherit the disease»