Sentences with phrase «transcription of genes»

«It's possible that microRNAs go into the bloodstream and affect the potential transcription of these genes in the sperm,» says Brian Dias at Emory University in Atlanta, Georgia, who led the work in mice.

Activation of the UPR induces the production of a family of basic leucine zipper - containing transcription factors that activate transcription of genes encoding functions to reduce the protein - folding load and increase the protein folding capacity of the ER.

In Class I engagement, Sox9 binds to the genome indirectly via the basal transcriptional complex, regulating transcription of genes for basal cell activities.

The novel variations, dubbed «multiple nucleotide length polymorphisms,» or MNLPs, altered transcription of the genes they were associated with as much as 11-fold.

They also show how the transcription activator protein helps RNA polymerase bind to the DNA helix at a specific site preceding a gene, and how the transcription activator protein helps RNA polymerase unwind the DNA helix to initiate transcription of the gene.

«Adding retinoids calls away retinoic acid receptors, which are then unable to aid transcription of the gene,» Fettig says.

Blau's group found that the daily changes in Rho1 activity are controlled by rhythms in transcription of a gene very similar to human Puratrophin - 1.

This strict selectiveness of sensory neurons is in part due to enhancers (DNA sequences that enhance transcription of a gene when bound by specific protein), which remain poorly understood.

Also, CAGE data can be used to identify in - vivo transcribed enhancers, which are remote elements that increase transcription of a gene, independent of their distance or orientation to the gene's promoter.

In addition to its structural role in epithelial junctions, beta - catenin activates TCF -4-mediated transcription of genes required for cell proliferation.

La Jolla, CA — BRCA - 2, a gene linked with breast and ovarian cancer, cooperates with male sex hormones to enhance its ability to activate transcription of genes, which may suppress...

PULLMAN — Researchers at Washington State University have identified a new class of DNA sequence variation in gene promoter regions that could help control the activity of genes.The novel variations, dubbed «multiple nucleotide length polymorphisms,» or MNLPs, altered transcription of the genes they were associated with as much as 11-fold.

These included sites involved in regulating gene activity during brain development and initiating the transcription of genes.

«Perhaps the methylation of the gene can be compared with a dimming switch, which regulates the transcription of the gene and thus the amount of the enzyme formed.

In Class I engagement, Sox9 binds indirectly to the DNA and regulates the transcription of genes involved in basal cell activities.

PRMT5 (protein arginine methyltransferase 5) is an enzyme that alters the structure of chromatin to suppress the transcription of genes and the production of proteins.

STAT3 (signal transducer and activator of transcription 3) is a protein that activates the transcription of genes in response to IL - 6, a signaling protein released by cells in response to injury and inflammation.

Notably, this ESC / E (Z)(Extra Sex Combs / Enhancer of Zeste) gene complex regulates epigenetic mechanisms that govern the transcription of genes into proteins in response to the environment — including sex hormones and stressors.

During the transcription of genes, for example, the cell briefly creates single strands of DNA that could accidentally be cut by Cas12a.

(DNA bound to histones may be inaccessible to the transcription machinery, preventing the transcription of these genes, while unbound DNA allows space for the machinery and the genes may be transcribed.)

SMAD proteins transduce signals from TGFβ ligands at the cell surface to the nucleus where they activate the transcription of genes that trigger apoptosis.

Our computational biology research is focused on genome analysis, with an emphasis on the identification and characterization of regulatory sequences controlling the transcription of genes.

In breast cancer cells, the ABL kinases activated the transcriptional coactivator TAZ and the transcription factor STAT5, which triggered the transcription of genes encoding factors that activate osteoclasts (cells that break down bone) and those that enhance the survival of breast cancer cells in the bone microenvironment.

In addition, the DHA and EPA found in fish oil have a powerful ability to enhance the metabolism and increase fat burning by positively altering the gene functioning through various mechanisms which include changing the makeup of cell membranes, altering the transcription of genes and influencing the levels of calcium within the cells.

Knotweed provides resveratrol, which may helps to prevent damage to DNA, influences the transcriptions of genes responsible for redox metabolism, and supports cellular health.

Epigenetic modifications of promoter regions that influence the transcription of genes coding for crucial protein products can be induced by the environment.