Sentences with phrase «tumour progression»
The phrase "tumor progression" refers to the growth and spread of a tumor (abnormal mass of cells) inside the body, which can lead to the worsening of the condition. Full definition
Mimicking the tumour microenvironment (TME): Angiogenesis in tumour progression.
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«Naked mole rats have an additional barrier in the way of tumour progression,» says Seluanov, who presented the results at the Strategies for Engineered Negligible Senescence meeting in Cambridge, UK, last week.
In addition, the results of the study have initiated a new therapeutic strategy based on the inhibition of the P45 - IKKα enzyme, a protein that is essential in the case of BRAF mutated tumours, for tumour progression.
«The new knowledge we have gained facilitates the design of prophylactic and therapeutic measures for delaying tumour progression and extending cancer - free periods in RDEB,» says Venugopal Rao Mittapalli, the first author of the study.
By identifying two cytokines, key factors in the recruitment of blood cells essential to the formation of new blood vessels, and above all by deciphering how these factors interact simultaneously with blood vessels, researchers at the University of Geneva (UNIGE) are highlighting an additional way of controlling tumour progression.
Abstract 102P: C.T. Harbison and colleagues from Princeton, USA, report that PD - L1 expression on NSCLC tumours may associate with other factors, including expression of immune genes, tumour progression markers, and driver mutations that may influence the likelihood of response to the human IgG4 PD - 1 immune checkpoint inhibitor antibody nivolumab.
Previous studies have suggested that both coffee and tea play an important role in modulating disease - risk in humans by suppressing tumour progression, decreasing inflammation and influencing estrogen metabolism, mechanisms that may be mediated by epigenetic changes.
Invasion of cancer cells into surrounding tissues has a causal role in tumour progression and is an initial step in tumour metastasis.
Although these results are an important step forward in understanding the mechanisms of tumour progression, more research is needed before this treatment can be applied to clinical practice.
Most of the studies have focused mainly on tumour cells, whilst the cells that form the stroma are the great unknown, in spite of different research groups proving that some components of stroma promote the tumour progression.