Sentences with phrase «type of leukemia»

There are several different types of leukemia one can suffer from which can change to potential outcome of one's life insurance application.

Researchers from Instituto de Medicina Molecular (iMM) João Lobo Antunes have found a mechanism through which certain types of leukemia resist chemotherapy, thus revealing novel molecular targets that may be used to improve the efficiency of this type of treatment.

Research carried out at the Division of Genetics at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) with support from the Institute for Human Genetics has now discovered another molecular cause for a particularly aggressive type of leukemia in infants.

Patients with a rare type of leukemia called acute promyelocytic leukemia (APL) have better outcomes than most leukemias because they can be treated with a very...

DNMT3A is among the most frequently mutated genes in an aggressive type of leukemia, and it plays a significant role in how this disease develops.

Patients with a rare type of leukemia called acute promyelocytic leukemia (APL) have better outcomes than most leukemias because they can be treated with a very effective drug that converts their cancer cells back to normal.

He noted that before physicians and scientists begin offering SSC transplantation in patients, additional research will be needed, including whether other types of leukemia cells will also be eliminated in the cell - propagation process.

Chemotherapy drugs, alone or in combination, are used to treat most types of leukemia.

And when transplanted to a petri dish, they gave rise to the more common type of leukemia cell.

The engineered cells contain an antibody - like protein known as a chimeric antigen receptor (CAR), which is designed to bind to a protein called CD19 found on the surface of B cells, including the cancerous B cells that characterize several types of leukemia.

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center have developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects.

Cancer Institute research highlights include innovative studies to develop individualized approaches for treatment and prevention of lung cancer; collaboration between medical and materials science researchers to develop treatments for various types of leukemia using nanotechnology to target only cancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor development.

AML is one of the most deadly types of leukemia and the most common type of acute leukemia in adults; it increases in frequency as we age.

A special type of leukemia, which is particularly difficult to treat and often occurs in very young patients, is the subject of research carried out by Prof. Robert Slany and his team at the Division of Genetics at FAU.

The new study, published March 14 in the Journal of Clinical Investigation, focused on a particularly aggressive form of B - cell acute lymphoblastic leukemia (B - ALL), the most prevalent type of leukemia in children and young adults.

Bone marrow transplants can cure types of leukemia and lymphoma because hematopoietic stem cells derived from the donor's bone marrow can develop into immune cells capable of killing the patient's tumor cells.

There are four main types of leukemia, two chronic and two acute: chronic myeloid leukemia (CML), chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL) and acute myeloid leukemia (AML).

The first gene therapies approved in the United States are treating patients with certain types of leukemia and lymphoma.

In addition to B - ALL, the findings have implications for other types of leukemia, such as acute myeloid leukemia and T - cell acute lymphoblastic leukemia, and other cancers where the loss of Ikaros function plays a role.

The modified T cells contain a protein known as a chimeric antigen receptor (CAR), which is designed to target the CD19 protein found on the surface of B cells, including the cancerous B cells that characterize several types of leukemia and lymphoma.

On August 30, the U.S. Food and Drug Administration approved a novel gene therapy for patients with a rare type of leukemia.

We hope that these new insights will allow us to increase our understanding of the molecular mechanisms that result in cancer and to more effectively treat this aggressive type of leukemia.»

These chromosomal translocations are common in various types of leukemia, so the researchers examined two types: acute promyelocytic leukemia, which often carries a translocation between the PML and RARα genes; and acute myeloid leukemia, which can harbor a translocation between the MLL and AF9 genes.

There is no known way to prevent most types of leukemia, though some types may be prevented by avoiding high doses of ionizing radiation, exposure to the chemical benzene, smoking and certain types of chemotherapy.

While they were able to block DOT1L directly using an inhibitor substance currently being tested in a clinical trial for a different type of leukemia, a direct drug - based inhibition of MLL proved impossible.

Half of the patients treated in this study responded to either ponatinib (typically used for certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the genetic alterations identified through sequencing.

The drugs used, pazopanib (top) and ponatinib, are typically used to treat kidney cancer and certain types of leukemia, respectively.

New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival.

The next steps in the research include determining whether the IGF2BP3 protein plays a role in other types of leukemia, and testing drugs or compounds that might inhibit the protein and effectively kill leukemia cells in patients.

A gene therapy treatment called CAR - T immunotherapy has been approved for use in a rare type of leukemia.

These findings provide renewed hope for developing new treatments for this aggressive type of leukemia.»

The researchers at Sandia and the university did molecular computer simulations to predict what mutations would produce that desirable result when introduced into the enzyme - drug L - ASN2, commonly used to treat certain types of leukemia.

In the new study, a team led by biochemist Björn Ingelsson and immunochemist Anders Rosén of Linköping University in Sweden investigated whether NETs might also spur the growth of cancerous white blood cells in one type of leukemia — something scientists had previously hypothesized.

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

We developed SomaticSniper to detect somatic mutations in whole - genome sequencing data while allowing for tumor contamination of normal cells that occurs in some types of leukemia.

Hungerford, a predoctoral fellow, was writing his doctoral thesis on chromosomes in a genetics lab at Fox Chase Cancer Center, and detected a tiny flaw in chromosomes from the blood cells of patients with a type of leukemia.

Dr. Collins treats patients with all types of leukemia — from the most common and straightforward cases to the rarest and most complex — as well as those with other hematologic malignancies and bone marrow diseases, including lymphoma, myelodysplastic syndrome, myeloma, and aplastic anemia.

It is approved by the U.S. Food and Drug Administration (FDA) for treating certain types of leukemia and is helpful in other conditions that require immunosuppressive therapy.

Several types of leukemia were characterized by exome sequencing, including chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), acute monocytic leukemia (M5 AML), and pediatric acute lymphocytic leukemia (ALL).

Several targeted drugs (e.g., imatinib [Gleevec ®], dasatinib [Sprycel ®]-RRB- are effective for treating CML because they attack cells with the Philadelphia chromosome, the genetic abnormality that is the hallmark of this type of leukemia.

Genetic variation has been found in other types of cancer, including lung cancer, kidney cancer, and some types of leukemia.

At UT Southwestern and Children's Health, we treat every type of leukemia in children and adolescents, from the most frequently occurring forms of the disease to the most rare.

For example, Penn's blood cancer trials employ a CAR targeting the protein CD19, which is found on the surface of B cells, including the cancerous B cells that characterize several types of leukemia and lymphoma.

And some people can live for decades after diagnosis, depending on the type of leukemia.

Do you have specific recommendtions for this type of leukemia?

The type of leukemia a dog has — chronic or acute — determines his prognosis and how successful treatment will be.