Sentences with word «urokinase»

Figure 8 (C) shows that kahweol - treatment induces a dose - dependent decrease in the levels of urokinase in HUVEC conditioned media, with an almost complete inhibition at 50 µM kahweol.

In an elegant but still unfolding story of molecular detective work, researchers hunting for a cause of chronic kidney disease have homed in on a protein known as soluble urokinase plasminogen activator receptor (suPAR).

Urokinase doesn't change that, to my knowledge.

It seems to stop cancer cells from reproducing and inhibits the enzyme urokinase from helping cancer cells grow.

Itoh et al. «Inhibition of Urokinase Receptor (uPAR) Expression by RNA - Cleaving Catalytic DNA (DNAzyme) Containing Antisense uPAR», Molecular Therapy, 5 (5): S134, 2002.

In addition, it also enhances the body's production of both plasmin and other clot - dissolving agents, including urokinase (endogenous).

T - PAs (tissue plasminogen activators) like urokinase (the drug), are only effective when taken intravenously and often fail simply because a stroke or heart attack victim's arteries have hardened beyond the point where they can be treated by any other clot - dissolving agent.

Urokinase comes along, carried on the surface of platelets and certain white blood cells, to finish the job.

is urokinase consumed by this process?)

I don't know the biochemistry in enough detail to say whether this is a really good metaphor (can urokinase only be activated if tPA has acted?

Everyone has urokinase plasminogen activator receptor (uPAR), a healthy molecule «tethered» in place to various types of cells.

Thrombosis recanalization by paeoniflorin through the upregulation of urokinase - type plasminogen activator via the MAPK signaling pathway.

tPA kicks off the process, and once it's started, urokinase does the rest.

This protease activates hepatocyte growth factor (HGF) and urokinase plasminogen activator (uPA), two proteins thought to be involved in the growth and motility of cancer cells, particularly carcinomas, and in the vascularization of tumors.

They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).