Sentences with phrase «vertebrate genomes»
"Vertebrate genomes" refers to the complete set of genetic material or DNA found in the cells of animals with a backbone, such as humans, dogs, fish, or birds. It includes all the instructions that determine the traits and characteristics of these animals. Full definition
Because of the great similarities between bone cancer in dogs and humans, we believe that our findings may contribute to an increased understanding of how bone cancer develops in humans,» said Kerstin Lindblad - Toh, professor at Uppsala University and Co-Director of the SciLifeLab and Director of Vertebrate Genome Biology at the Broad Institute.
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«Our study reveals a spectrum of methods that nature uses to allow organisms to adapt to different environments,» said senior author Kerstin Lindblad - Toh, Scientific Director of Vertebrate Genome Biology at the Broad Institute: «These mechanisms are likely to be also at work in humans and other vertebrates, and by focusing on the remarkably diverse cichlid fishes, we were able to study this process on a broad scale for the first time.»
ENSEMBL makes available substantial and diverse transcript information, including the CCDS [13, 41], Human and Vertebrate Analysis and Annotation (HAVANA)[42], Vertebrate Genome Annotation (Vega)[43], ENCODE data [12] and the GENCODE gene and transcript sets [15].
To identify such mutations, we compared the 80 vertebrate genomes available so far and identified variants located in non-coding regions highly conserved through evolution.
A rush of new research has found evidence that some RNA viruses made their way into vertebrate genomes millions of years ago
«It was exciting to see that half of the domestication signals in the genome point to genes that have to do with brain development and function», says professor Kerstin Lindblad - Toh, senior author and director of SciLifeLab Uppsala, and scientific director of vertebrate genome biology at the Broad Institute.
The performance of our workflow was assessed on vertebrate genome assemblies of various qualities (platypus, pig, horse, dog, mouse and human).
Fugu — the poisonous puffer fish sought after by brave suchi - eaters — has the smallest known vertebrate genome.
Yet trying to understand the genetic explanations of such questions is surprisingly difficult considering most vertebrate genomes, including our own, are made up of literally billions of DNA bases that can determine how an organism looks and functions,» says Castoe.
A new look at a virtual zoo - full of animals, from hummingbirds to bats to elephants, suggests that many vertebrate genomes have the same accordion - like properties.
«It's by far the oldest vertebrate genome we have so far,» says Johannes Krause of the University of Tübingen, Germany, who was not involved in the study.
The elephant shark has the smallest genome among cartilaginous fishes, and has been shown to be the slowest evolving vertebrate genome, according to a new study in the journal Nature.
Indeed, the BDV discussed earlier inserted some of its sequences into vertebrate genomes approximately 40 million years ago [56], and presence of these sequences correlates with disease resistance to BDV.
They report that the genes encoding the different subunits of PDE6 in cones and rods arose from ancestral genes that duplicated in the early vertebrate genome doublings, and further expanded in teleosts due to the extra genome duplication that took place in this lineage.
Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation.
Principal Investigator: Kerstin Lindblad - Toh Scientific Director of Vertebrate Genome Biology at the Broad Institute Broad Institute of MIT and Harvard
Unlike the previous studies that focused on certain species or a particular RNA virus, Skalka went broad: She and her colleagues surveyed every vertebrate genome available, 48 in all, and looked for hints of 5666 RNA viral sequences from 38 known families and nine genera that were unclassified.
«Vertebrate genomes are typically on the larger side, so it takes a lot of computational power to assemble them,» says Card.
But now that three vertebrate genomes have been sequenced — human, mouse, and pufferfish — geneticists are re-thinking their appraisal.
The more we understand about how natural variation in the vertebrate genome shapes the development and function of the brain, the better insight we can have into how behavioral patterns evolve, and how disruption to neurogenetic pathways can lead to brain and behavioral dysfunction.
Consequently, ERVs make up large portions of vertebrate genomes and represent a record of past host - retrovirus interactions.
According to recent estimates, while over 30 % of vertebrate genomes is transcribed (2), only 1 % consists of coding genes, suggesting that the rest must be various types of non-coding RNA genes.
Studies The Puppy Up Foundation helped fund with The Broad Institute: Title of Study: Osteosarcoma Grant Awarded: $ 20,000 Principal Investigator: Kerstin Lindblad - Toh Scientific Director of Vertebrate Genome Biology at the Broad Institute Broad Institute of MIT and Harvard Title of Study: Mast Cell Tumors Grant Awarded: $ 20,000 Principal Investigator: Kerstin Lindblad - Toh Scientific Director of Vertebrate Genome Biology at the Broad Institute Broad Institute of MIT and Harvard