Sentences with phrase «viral sequences»

But the researchers were analyzing viral sequences to address different questions — such as the viral mutation rate — or only looked at samples isolated in the early days of the outbreak.

Unlike the previous studies that focused on certain species or a particular RNA virus, Skalka went broad: She and her colleagues surveyed every vertebrate genome available, 48 in all, and looked for hints of 5666 RNA viral sequences from 38 known families and nine genera that were unclassified.

Viral discovery is performed on human, animals, biologics, and environmental samples using viral particle enrichment, random nucleic acid amplification, and deep sequencing followed by bioinformatics analysis for the presence of viral sequences.

However, viral sequences found in genomes are often fossils of long - ago infections that can no longer reproduce independent virus particles that can then infect additional bacteria.

Although the researchers don't know whether the embedded viral sequences have a function, they suspect they are helpful to the animals — otherwise, they wouldn't have endured through millions of years of evolution.

Nineteen of the species, including a squirrel, a small bat, a zebrafish, and a human had RNA viral sequences embedded in their DNA.

Using a reverse - genetics system, in which specific viral sequences are manipulated within the context of a full - length infectious clone of the virus, they have been defining the roles of particular viral components in influencing DENV and ZIKV infection in mice and human cells.

The team looked for evidence of XMRV in several ways, including fishing for viral sequences with the ultrasensitive PCR assay, trying to grow infectious virus in cell cultures, and scouring the blood for antibodies to viral proteins.

We used massively parallel viral sequencing to understand how and when EBOV entered human populations in the 2014 West African outbreak, whether the outbreak is continuing to be fed by new transmissions from its natural reservoir, and how the virus changed, both before and after its recent jump to humans.

The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers.

In collaboration with the NIH and Avi - Mex, a Mexican veterinarian company, he and his team obtained 58 whole - genome sequences from influenza A viruses collected in the Mexican pigs and found viral sequences previously not known to exist in Mexico or in any other part of the world.

«The challenge will now be to use ancient viral sequences for looking back in time, which may prove insightful for predicting the long - term consequences of newly emerging viral infections.

She has contributed to widely varying fields — such as viral sequencing, information theory, rural disease surveillance, and education efforts in West Africa — to create comprehensive approaches for detecting, containing, and treating deadly infectious diseases.

Viral sequences integrated into plant genomes.

Inflammatory breast cancer in U.S. women has been found to have a higher incidence of viral sequences (71 %) than other sporadic breast cancers.

Because Ebola diagnostics and some therapeutics like vaccines are based on the specific viral sequence, it is important for researchers to have the most up - to - date virus genome sequence possible.

The authors analyzed changes in the viral sequence and conclude that the current outbreak probably resulted from the spread of the virus from central Africa in the past decade.

With gene - editing tools such as CRISPR, scientists can now eliminate immune - provoking sugars from the surface of pig cells, introduce human genes that regulate blood coagulation to prevent dangerous clots, and snip out viral sequences that some fear could infect a human host.

One sample batch returned a promising lead: a viral sequence belonging to the Circoviridae family.

By revealing similar elements in plants» DNA, genome sequencing has liberated developers from having to borrow the viral sequences.

But in five years when the cost is under $ 500 and an amateur scientist catches swine flu and decides to publish the viral sequence on his blog, the media outcry may be significant enough to stifle even the safe activities of the community.

McClure's team used a PCR machine — which copies and amplifies scraps of DNA — to search for two viral sequences, one from XMRV and the other from a closely related virus.

Analysis of the viral sequences suggests that one of these introductions, which has been linked to several EVD cases in Monrovia, including health care workers at Redemption Hospital, likely led to the largest wave of cases in Liberia.

First generation of infectious virus particles in E.coli from a plasmid encoding the viral sequence.