Sentences with phrase «wider analysis»

As producers of these data we reserve the right to be the first to publish a genome - wide analysis of the data we have generated.

Led corporate wide analysis and implementation of excess and obsolete inventory reductions.

Among individuals with two divergent mitochondrial haplotypes (mt - haplotypes), the genome - wide analyses revealed significant differences in nuclear allele frequencies.

The genome - wide analyses showed that Cpf1 was highly specific, showing fewer off - target cleavage sites (6 for LbCpf1 and 12 for AsCpf1), compared to Cas9, cleaving at > 90 sites in the human genome (Fig. 1a).

«Genome - wide analysis allowed us to identify a gene, VNN - 1, whose expression discriminated between good and poor responders to systemic corticosteroid treatment,» said Gurjit Khurana Hershey, MD, PhD, senior author and director of Asthma Research at Cincinnati Children's.

Genome wide analysis of lymphomas of the thymus in these mice with the truncated Rag2 protein revealed a surprise: numerous off - target DNA rearrangements, causing deletions, noted Roth.

Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton, added: «This study forms part of a larger programme of work addressing risk factors for fracture across the lifecourse, and demonstrates the importance of the University of Southampton and MRC Lifecourse Epidemiology Unit in leading large, UK wide analyses on the internationally leading UK Clinical Practice Research Datalink dataset.

Tengvall K, Kierczak M, Bergvall K, Olsson M, Frankowiack M, et al. (2013) Genome - Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis.

There's a temptation to read a lot into the play, but Mullarkey's drilling down to the detail and rhythm of soldiers» training defeats wider analysis.

To identify the genes that give rise to the palette of human skin tones, Crawford et al. applied genome - wide analyses across diverse African populations (see the Perspective by Tang and Barsh).

For Indonesia, as the analysis of deforestation and protected area effectiveness has been limited by data availability and geographical scope, the nation - wide analysis conducted in the study is useful to better understand the factors affecting the rate of deforestation and the measures needed to tackle it.

«Underpinnings of drought tolerance in plants: Genome - wide analysis elucidates drought - tolerance system in Arabidopsis.»

February 14, 2013 Humans and chimps share genetic strategy in battle against pathogens A genome - wide analysis searching for evidence of long - lived balancing selection — where the evolutionary process acts not to select the single best adaptation but to maintain genetic variation in a population — has uncovered at least six regions of the genome where humans and chimpanzees share the same combination of genetic variants.

Genome - wide analysis yields new loci associating with aortic valve stenosis.

According to a nation - wide analysis by Monty Neill, executive director of the National Center for Fair & Open Testing (FairTest), states with high - stakes tests do not show a clear pattern of improved performance on the NAEP relative to states without such tests.

The collaboration would produce at least one advanced proof - of - concept application to allow wide analysis within the member firms prior to a go / no go decision on developing and implementing a live application.

«In the current study, using a genome - wide analysis of DNA methylation, we identified a few PPARα target genes that underwent ligand - activated PPARα - dependent DNA demethylation during the perinatal period and whose DNA methylation status persists into adulthood,» explains a corresponding author Koshi Hashimoto.

Genome - wide analysis reveals specificities of Cpf1 endonucleases in human cells.

Genome - wide analyses showed a Wnt3a - dependant release of Setdb1 from the promoter of selected target genes upon myoblast terminal differentiation.

Large scale sequencing approach and genome wide analysis can be applied on different economic crops for better understanding their evolutionary process and specific traits, providing unique opportunities for further applications.»

They used sophisticated genetic tools to conduct comprehensive genome - wide analyses on the genetic markers of 18 Bene Israel individuals.

for article Genome - wide analysis identifies 12 loci influencing human reproductive behavior.

According to See Change Strategy, a think - tank that conducted an industry - wide analysis of the medical marijuana trade, the current national market for cannabis is $ 1.7 billion.

Ultimately, it's really a mix of company - specific news flow analysis as well as market - wide analysis.

Last year, a wider analysis of over 1,200 business sites and 700 companies found that the median site reaped $ 14 in returns for every $ 1 invested.

With the recent development of specialized methods for genome - wide analysis of aDNA, «the power of archaeogenetics has really been unleashed,» says Krause.

Sure enough, in 2011 he reported on a genome - wide analysis of blood samples taken from 40 men who participated in a British study of people born in England in 1958.

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

Using genome - wide analyses, the MDC researchers found that GRHL2 regulates a defined gene program.

The researchers performed genome - wide analysis of nasal epithelial cells collected from children experiencing acute asthma exacerbation.

Genome - wide analysis of 2000 Africans identifies and functionally characterizes pigmentation loci.

They also performed comparative and genome - wide analyses, which provide insights into the evolutionary history of Asterids, a subgroup of flowering plants that includes potatoes, tomatoes and coffee.

The researchers, including postgraduate students Miaolin Chen at Shanghai Jiao Tong University and Deborah Devis at the University of Adelaide's Waite campus, performed a genome - wide analysis of potential pollen allergens in two model plants, Arabidopsis thaliana (thale cress) and rice by comparing those results among 25 species of plants ranging from simple alga to complex flowering plants.

Conducting the first large - scale, genome - wide analyses of ancient human remains from the Near East, an international team led by Harvard Medical School has illuminated the genetic identities and population dynamics of the world's first farmers.

«Importance of transcription in animals has been underestimated by system - wide analyses.»

«Using genome - wide analysis, we demonstrate that this factor is able to specifically regulate cell proliferation in these tissues, and it does it by means of the AURKA protein that is involved in the control of cell division,» says Serrano.

The study, which is the most powerful genetic study of anorexia nervosa conducted to date, included genome - wide analysis of DNA from 3,495 individuals with anorexia nervosa and 10,982 unaffected individuals.

In the first study to run a genome - wide analysis of Short Tandem Repeats (STRs) in gene expression, a large team of computational geneticists led by investigators from Columbia Engineering and the New York Genome Center have shown that STRs, thought to be just neutral, or «junk,» actually play an important role in regulating gene expression.

They then used genome - wide analysis to search for genes switched on by KLF4 at a late stage of reprogramming.

Even more complicated will be linking telomere length to genome - wide analyses, which is on the horizon.

The genome - wide analysis was led at OIST by researchers in the Molecular Genetics Unit.

«This was what you call a sort of fast - track phase,» Hakonarson says about the new study, in which he and his team identified and characterized only the strongest signals in the genome - wide analysis.

«The results of our study speak to the evolutionary origins of obesity and provide new targets to understand the polygenic nature of obesity in a unique model system,» according to the study, «Genome - Wide Analysis of Starvation - Selected Drosophila melanogaster — A Genetic Model of Obesity.»

Yet it is small enough for high - resolution genome - wide analysis.»

Here, using genome - wide analyses of X, Y, autosomal and mitochondrial DNA, in combination with extensive population genetic simulations, we show that low observed Y chromosome variability is not consistent with a purely neutral model.

Genome - wide analysis of variance (ANOVA) revealed that germline SNPs / CNVs and somatic CNAs influenced > 39 % of gene expression probes, roughly half acting in cis and half in trans.