Sentences with phrase «with docetaxel»

No evaluable data were available for the comparison with docetaxel in patients in whom prolongation of life was the primary treatment goal.

The new analysis extends follow - up significantly; it includes 790 patients randomized to either ADT alone (393 patients) or in combination with docetaxel (397 patients).

«When we embarked on this study, early clinical trials and laboratory studies supported the possibility (or hypothesis) that earlier therapy in appropriate patients with docetaxel, used in combination before hormonal resistance occurred, could have greater benefit, but required proof in a definitive study.

The study enrolled 790 men newly diagnosed with metastatic disease; they were randomized to receive ADT alone or ADT with docetaxel (brand name Taxotere ®) over 18 weeks.

A previous interim analysis of the CHAARTED trial showed a survival benefit with docetaxel added to ADT, but there were a low number of events at that point.

DENVER — Nivolumab (NIV), a checkpoint inhibitor approved for all squamous and non-squamous non-small cell lung cancer (NSCLC) patients in 2015, is not cost - effective when compared to treatment with docetaxel (DOC), chemotherapy medication.

However, subset analyses of phase III trials suggest that patients with EGFR mutation - positive NSCLCs do not benefit from immunotherapy compared with docetaxel.

In the TAILOR study, investigators randomized patients to either erlotinib 150 mg / day or chemotherapy with docetaxel 75 mg / m2 or 35 mg / m2.

Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormonereleasing hormone in combination with docetaxel.

The main purpose of this study is to find out more about the side effects of the study drug, MM - 121, when combined with the study drugs, docetaxel or pemetrexed, and to learn if cancer cell growth (disease progression) is delayed in people taking MM - 121 with docetaxel or pemetrexed.

Researchers are also trying to learn about: - The level of MM - 121 that remains in the human body at different time points when MM - 121 is combined with docetaxel or pemetrexed - The relationship between the biomarker, heregulin, and cancer cell growth (disease progression) in people dosed only with docetaxel or pemetrexed.