Working with proteins called zinc finger nucleases and TALENs, Zhang attempted to edit the genomes of mammalian cells with a view to engineering them. (vilcek.org)
The use of CRISPR / Cas9 for gene editing has expanded since its adaptation for use in mammalian cells in 2012 - 2013. (blog.addgene.org)
The system can change single RNA nucleotides in mammalian cells in a programmable and precise fashion. (broadinstitute.org)