"Mouse fibroblasts" refers to a type of cells that are found in mice and are responsible for producing and maintaining the connective tissue in their bodies. Full definition
Indeed, a recent report has demonstrated that the small molecule, kenpaullone could replace KLF4 in reprogramming mouse fibroblasts into iPS cells [32]. (journals.plos.org)
Imagine researchers» excitement, then, when Kyoto University's Shinya Yamanaka reported last year that his group had created embryolike cells directly, without transferring chromosomes, simply by injecting mouse fibroblast cells with four genes that are active in embryonic cells but not in adult ones. (scientificamerican.com)
They found that the combination of the transcription factors Brn3a plus Ngn1, or Brn3a plus Ngn2, reprogrammed a significant percentage of the embryonic mouse fibroblasts into what looked — and acted — like mature DRG - type sensory neurons. (sciencedaily.com)