We use our proprietary technology platform to advance the next generation of genetic medicines, designed to intervene at the root of the problem by targeting the expression of disease - causing genes. (silence-therapeutics.com)
Class - specific inhibition of Gq - mediated signaling was produced in the hearts of transgenic mice by targeted expression of a carboxyl - terminal peptide of the α subunit Gαq. (science.sciencemag.org)
If approaches could be developed that specifically target expression of both CCR5 and CXCR4 on CD4 + T cells, virus entry should be inhibited more effectively. (journals.plos.org)