Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. (inmg.fr)
Whitehead Institute researchers have elucidated how the growth - regulating metabolic pathway known as mTORC1 (for mechanistic target of rapamycin complex 1) senses the amino acid arginine. (wi.mit.edu)
In cancer, PAT function has been related to the amino acid - sensing engine that drives activation of the mammalian target of rapamycin complex 1 (mTORC1), which is an important target for existing and new anti-cancer drugs.» (sciencedaily.com)