These two histones thus have a key role of epigenetic silencing of tumor suppressor genes in breast cancer (and likely other cancers), suggesting that they may represent new therapeutic targets. (massgenomics.org)
Off - target mutations in tumor suppressor genes, for example, can cause cancer. (sciencedaily.com)
Researchers have identified a protein that activates the well - known tumor suppressor gene p53 to prevent the division of cells that have damaged DNA. (hhmi.org)