Sentences with phrase «apoptotic cells»
Apoptotic cells are cells in our body that undergo a natural process of programmed cell death. This process helps keep our body healthy by removing old, damaged, or unnecessary cells. Think of it as a way for our body to clean up and maintain a balanced and functional system. Full definition
Bcl - 2 protein expression is topographically restricted in tissue characterized by apoptotic cell death.
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Treatment of lung cancer cell lines with mebendazole caused mitotic arrest by depolymerization of tubulin, followed by apoptotic cell death.
Caspases are enzymes that play key roles in apoptosis, necrosis and inflammation, and their activation is necessary for apoptotic cell death.
He worked as a graduate student in the Kapahi lab and his research was focused on characterizing apoptotic cell clearance factors in the intestinal tract of fruit flies.
During programmed cell death, apoptotic cells flag themselves for elimination by moving a specific cell membrane component known as phosphatidylserine (PS) from the inner membrane to the cell surface, setting them up to be engulfed.
This toxin causes extensive apoptotic cell death in both the midgut epithelium and circulating hemocytes of caterpillar hosts.
She recently co-authored a paper with Kantorow and research colleagues titled «Integrin αVβ5 - mediated removal of apoptotic cell debris by the eye lens and its inhibition by UV - light exposure,» published in the Journal of Biological Chemistry.
* please note this kit can not be used for the amplification of apoptotic DNA (160 - 170 bp), please see our TruePrime ™ apoptotic cell - free DNA amplification kit.
In addition, our data evidence that LA via the Rho - associated kinase - mediated pathway promotes stress fiber formation, which exerts a main role in the morphological changes associated with apoptotic cell death.
Annexin V - FITC staining was used as a marker for apoptotic cells, while PI staining was used as an indicator of necrotic cells that had lost membrane integrity.
«Basically it is a mutation that makes potential stem cells, or precursor cells, susceptible to apoptotic cell death pathways.
At the time, a handful of genes were known to be involved in the engulfment of apoptotic cells but these were not sufficient to explain the whole process.
But this process is important because «if the apoptotic cells are not properly cleared... it will affect the cell death activation» in organisms like worms and cause persistent inflammation and autoimmune responses in humans.
Enzo Life Science's GFP - CERTIFIED Apoptosis / Necrosis Detection Kit detects four distinct cell states: viable cells, early apoptotic cells, late apoptotic cells, and necrotic cells.
Mitotic cells have spindles; apoptotic cells have blebs.
Known as the phosphatidylserine receptor, or PSR - 1, the molecule can locate and clear out apoptotic cells that are pre-programmed to die as well as necrotic cells that have been injured and are causing inflammation, said CU - Boulder Professor Ding Xue, who led one study and co-authored the other.
For example, by engineering PA - GFP tagged to a mitochondrial matrix protein (mito - PAGFP) the Youle Lab was able to visualize and quantify the fusion dynamics of mitochondria in healthy and apoptotic cells (9).
This effect on growth inhibition was not due to alterations in cell cycle (Supplemental Fig. 5) nor a significant increase in the apoptotic cell populations, suggesting that RIPK2 inhibition of proliferation is independent of cell cycle or apoptotic changes.
Arrows point to apoptotic cells.
Apoptotic cells are stained green.
This research is currently dissecting the proteolytic components of the intracellular pathway that lead to apoptotic cell death.
In the calorie - restricted STZ rats, comparable findings were restricted to individual islet area and percentage of apoptotic cells.