Sentences with phrase «at atomic resolution»

The final outcome is a detailed 3D view of the molecular structures at atomic resolution.

Furthermore, it opens the way to capture the dynamics of proteins in real time at atomic resolution, which has been impossible with standard techniques until now.

In 1990, Henderson was the first to use an electron microscope to produce «a three - dimensional image of a protein at atomic resolution.

«Alzheimer fibrils at atomic resolution: Fundamental structural difference to earlier models.»

Twelve years later, he and his team succeeded in developing the NMR techniques for capturing a molecule in action, morphing into different shapes at atomic resolution.

That work triggered a close race between the Cambridge University group and a rival team at MIT in deciphering tRNA's 3D structure at atomic resolution with x-ray crystallography, with the two labs publishing results within 2 weeks of each other.

Researchers have gone on to study «proteins that cause antibiotic resistance» and to produce three - dimensional images of the Zika virus at atomic resolution, permitting scientists to hunt for weaknesses that new pharmaceuticals could exploit.

On page 206 of this issue, Han et al. report images of halogen bonding at atomic resolution (4).

Study co-author Petra Fromme, professor in ASU's Department of Chemistry and Biochemistry, echoes the importance of the new study: «This paper is very exciting as it is the first report of time resolved studies with serial femtosecond crystallography that unravels details at atomic resolution,» said Fromme.

«When combined with previous work, it is remarkable now to be able to assemble a true molecular movie of the photocycle of this blue light detector in bacteria at atomic resolution, with the intermediate structures appearing and fading in the correct sequence.

The achievable laser light wavelength corresponds to the size of an atom, meaning that the X-rays can be used to make pictures and films of the nanocosmos at atomic resolution — such as of biomolecules, from which better understandings of the basis of illnesses or the development of new therapies could be developed.

It is powerful because an AFM can generate images at atomic resolution with angstrom scale resolution height information, with minimum sample preparation.

The PhD program offers structured, state - of - the - art training in signal transduction and a wide spectrum of techniques and approaches ranging from the understanding of molecules at atomic resolution level to in vivo studies, to the development of bioinformatics methods and mathematical modelling.

Several more researchers presented their work during the day, including protein synthesis at atomic resolution, bio-imaging opportunities at synchrotrons, multi-dimensional imaging during plant cell differentiation, how to use electron cryomicroscopy for in situ structural biology, and how structured illumination microscopy can offer insights into the regulation of mammalian meiosis.

«Fitzpatrick and colleagues have paved the way for development of new drugs designed to prevent tangle formation by deciphering the molecular structure of the «tau» protein filaments that make up the tangles at atomic resolution.

«Seeing this drug bound to its intended human protein target at atomic resolution was mind - blowing,» said Frost, an assistant professor of biochemistry and biophysics at UCSF.

Scanning transmission electron microscopy has become a mainstream technique for imaging and analysis at atomic resolution and sensitivity, and the authors of this book are widely credited with bringing the field to its present popularity.

GERBER: Our sole idea in developing AFM was to image nonconductive surfaces, such as ceramics or biological materials, at atomic resolution by scratching a very fine needle on a long arm, or cantilever, over that surface.

Structure of the HIV Protein Shell Reveals Clues for New Therapies - «No one had been able to visualize the CA hexamer at atomic resolution,» says Professor Mark Yeager.

A European research team and a team from the United States (Massachussetts Institute of Technology in cooperation with Lund University) have simultaneously succeeded in elucidating the structure of the most disease - relevant beta - amyloid peptide 1 - 42 fibrils at atomic resolution.

«Additionally, while previous studies of dynein have revealed the molecule's two different static conformations, our animation visually depicts one plausible way that the protein can transition between those shapes at atomic resolution, which is something that other simulations can't do.

But in 1990, Richard Henderson succeeded in using an electron microscope to generate a three - dimensional image of a protein at atomic resolution.

Then in 1990, after 15 years» work refining sample preparation and electron detection, Henderson succeeded in using an electron microscope to create an image of a large bacterial cell membrane protein called bacteriorhodopsin, and do it at atomic resolution.

In a joint project between the Swiss Federal Institute of Technology in Zurich, the University of Lyon, and the Goethe University in Frankfurt am Main, in cooperation with colleagues at the University of Irvine and the Brookhaven National Laboratory, researchers have succeeded in determining the structure of a beta - amyloid peptide 1 - 42 fibril at an atomic resolution.

This was made possible by a combination of nuclear magnetic resonance spectroscopy (NMR) and electron paramagnetic resonance spectroscopy (EPR), two procedures that make it possible to characterise the structural configuration of a protein at atomic resolution.

For example, he co-invented a widely used technique for locating impurity atoms in nanocrystals and published the first observation of dislocation kinks, at atomic resolution.

X-ray crystallography allowed scientists to «see» the structure of matter — whether it was molecular or otherwise — at atomic resolution.