Sentences with word «biomarker»

The existing consortium project Nanomax pursues the realization of ultra-sensitive sensor platform aimed at the quantitative detection of biomarkers of cancer (breast cancer, colorectal cancer) and viral (hepatitis C virus HCV and its mutants) in biological fluids.

Video — Dr. Luda Diatchenko, McGill University, DriverMap in the search for Biomarkers for Chronic Pain (3:09)

The pre-consortium will identify unmet needs for the use of biomarkers in developing new treatments for people with Crohn's disease.

Glycan structure alterations have been identified as biomarkers for cancer and multiple cellular processes.

However, Grigsby says the idea of identifying biomarkers in breath could be applied to monitoring various aspects of health, such as fatigue, in commercial pilots too.

We describe the assessment of circulating brain - enriched microRNAs as potential biomarkers for Alzheimer's disease (AD)»

The overall objective is to define molecular predictors and correlates of durable clinical remission and the development of new biomarkers of immune tolerance and regulation that will reliably guide clinical decisions to taper immunosuppressive medications.

Researchers have been working to develop better biosensors that could quickly, accurately and automatically detect everything from cancer biomarkers in the blood to harmful bacteria in the environment.

In a report published June 28 in the Journal of General Internal Medicine, the research team describes how these interventions reduced overuse of troponin and other biomarker testing without compromising patient care.

Protein biomarker discovery for disease onset and progression, drug treatment and toxicity using mass spectrometry and array - based techniques

From 2006 to 2008, the DISC06 Follow - Up Study evaluated the effect of diet intervention during puberty on biomarkers associated with breast cancer risk among a subgroup of 260 DISC women ages 25 — 29 years (34, 35).

Research finds biomarkers in CFS sufferers that present a «metabolic signature» similar to that of animals in hibernation.

The translation of embracing process between an antibody and its antigen has a wide range of use in medical applications such as disease biomarkers detection and drug testing and discovery.

Furthermore, beyond weight loss, this dietary approach also improves other biomarkers such as cholesterol and hemoglobin A1c.

Genetically reprogramming late - stage human cancer cells to a stem - cell state enabled them to force the reprogrammed cells to progress to an early cancerous state, revealing secreted blood biomarkers of early - stage disease along the way.

They found that in all nine cases, their data matched the outcomes seen in patients, as measured by clinical protein biomarkers found in the bloodstream, which are used by doctors to determine whether a drug is killing the tumor cells.

Therefore, we undertook a preliminary study to assess the association of plasma inflammatory biomarkers with an overall AD polygenic risk score as well as with an inflammation - specific AD polygenic risk score in a sample set of 93 AD cases.

Kwon and her colleagues also looked at specific biomarkers of health, like blood pressure.

In efforts to enhance pre-clinical drug testing, Thomas Gaddy of the University of Southern California, Los Angeles, and colleagues in the research group of Professor Stacey Finley investigated a potential predictive biomarker for a type of cancer drug known as anti-angiogenic therapy.

Recent research identified biomarkers associated with inflammation that are elevated in HCM patients.

For the FAU report, the researchers looked at weight and height measurements as well as biomarkers such as blood pressure, cholesterol, triglycerides, hemoglobin A1C, body fat percentage and waist circumference.

Future studies will focus on developing biomarkers capable of making early predictions on whether patients will develop a severe form of the disease.

We utilize our proprietary single cell CTC platform to develop blood based biomarkers for solid tumor indications with our pharma partners.

And closely related to that need is the need for better biomarkers which can improve the measures of risk, the diagnosis, the progression, and importantly, as we will come to by the end of the talk, serve as an important opportunity to speed clinical trials of therapeutic candidates.

«This hampers integration of lipidomics into systems biology, and addressing it will improve our fundamental understanding of lipid biology, help identify new drug targets for therapy and discover lipid biomarkers from disease cohorts.»

The researcher also looked at several biomarkers related to brain health, which included (BDNF) brain - derived neurotrophic factor, a tiny molecule that's involved in memory and learning.

The ability to detect cardiac biomarkers at ultra-low levels is advancing the future of heart health.

Jerskey's most recent research involved the utility of neuroimaging techniques in identifying early biomarkers of disease, in addition to research exploring the subtle neuronal changes either to differentiate patient populations or to track changes over time.

«This gives us an underlying candidate biomarker panel that provides information on the subsequent clinical outcome or therapeutic efficacy, which can be validated to yield a final panel, then translated into say, an ELISA - based kit or some other immunodiagnostic format in the clinical setting,» says Dorfman.

More importantly, they also identified a few proteins that previously were not known to be HCC - related, opening possibilities for candidate biomarker development.

«We are proposing that the disease be defined in living people by evidence of brain pathology using biomarker studies, either brain imaging or body fluid examination, and that clinical symptoms should be regarded for what they are — a product or result of the disease, as opposed to the definition of the disease,» said lead author Dr. Clifford Jack, Jr. of the Mayo Clinic.

«Extrapolating our findings, our extremely conservative estimate is that there were 1.7 million individuals with a false - positive cardiac biomarker test in the U.S. over those two years,» Dr. Makam said.

Yes, I recommend magnesium and iodine for general health, but improving general health will usually improve biomarkers like LDL.

So the researchers have identified new molecular biomarkers that are relevant in melanoma diagnosis, prognosis and susceptibility.

Professor Andrea Laghi, Professor of Radiology at the University of Rome and principal investigator of the study, said: «The identification of new, accurate imaging biomarkers such as TexRAD analysis of MR images for early assessment of first - line cancer therapy response (predominantly to shrink the tumor before the main treatment) could be helpful in refining bowel - cancer patient management, providing a better targeting of preoperative therapy.»

Researchers at SciLifeLab / Uppsala University have, together with researchers from Turku and Bergen, discovered a new biomarker which makes it possible to identify women with uterine cancer who have a high risk of recurrence.

Nightingale's comprehensive blood biomarker analysis also supports the study of molecular signatures for risk factors, as well as the effects of dietary and drug interventions.

He is now fashioning the lab's multidots — tiny crystalline beads encapsulated in a special coating — into an actual product to detect multiple biomarkers on tumor cells.

But the shift towards detecting biomarkers by neuroimaging or monitoring gene expression has drawn criticism.

In addition, individuals with stage B HF had greater circulating concentrations of cardiac stress biomarkers levels, putting them at increased risk for death.

Scientists have been laboring to detect cancer and a host of other diseases in people using promising new biomarkers called «exosomes.»

Using biomarker data to adjust estimates of the distribution of usual intakes for misreporting: application to energy intake in the US population.

Lipotype offers high quality lipid analysis services with its Lipotype Shotgun Lipidomics Technology for a wide range of customers and applications including biomarker identification for clinical researchers, pharma and biotech companies, functional food development for the food industry, claim support for the cosmetics industry, as well as for the small - scale profiling needs of academic researchers.

About half of Quanterix's current applications are linked to neurology, and many researchers using their platform measure biomarker concentrations in both CSF and blood.

In addition, the relative abundance of Enterococcus in the healthy control group was significantly higher than in thenon - infectious group and infectious group that can be used asa potential diagnostic biomarker for diarrhea.

To this end his lab currently oversees three NIH - funded clinical trials that focus on biomarker development in cerebrovascular and lymphatic diseases.

Our research agenda includes advancing biomarker research, understanding why those under 50 are increasingly diagnosed with colon cancer, decreasing late - state diagnosis of high - risk populations, closing the referral gap for screening and diagnostic testing, and advancing long - term survivorship psychosocial concerns.

Genomic databases can be vast, given that the human genome comprises some 20000 genes, and so such an approach can, they suggest, dramatically decrease the number of features that must be analyzed to find useful biomarkers.