Sentences with phrase «calcium release»

Moreover, because calcium pumping requires energy, the low levels of calcium release also lower the metabolic demands of making a continuous, hour - long mating call.

Further, supplementation can suppress her natural calcium releasing hormones so that when she really needs extra calcium during nursing, she will not have the proper hormone balance to get it.

This new direction in the field of muscle fatigue is exciting to me because my work for the past 15 years has focused largely on the regulation of intracellular calcium release in cardiac muscle.

When the parathyroid glands release more parathyroid hormones, it causes the bones to release more calcium into the blood and reduces the amount of calcium released by the kidneys.

Parathyroid hormone signals the bones to release calcium into the blood, and signals the kidneys to decrease the amount of calcium released in the urine.

The findings reveal a causal chain of events whereby the decreased levels of wolframin protein destabilize the endoplasmic reticulum (causing endoplasmic reticulum stress), thereby reducing calcium release.

First, mild endoplasmic reticulum stress and impaired calcium release seriously disturbed mitochondrial dynamics, thus providing an explanation as to why alterations in the endoplasmic reticulum could lead to impaired mitochondrial dynamics.

The virus - coated bone tricked the body into infusing it with blood vessels and allowing it to regulate calcium release.

«The small amount of calcium released per stimulus is the key element that permits the calcium pumps in midshipman swimbladder muscle to keep up over long periods of high - frequency stimulation,» Rome explains.

«The combination of fast calcium pumping and small calcium release permits the midshipman to maintain the correct balance of calcium ions during its long - lasting mating call,» Rome says.

Liu, K.Q., Bunnell, S.C., Gurniak, C.B. & Berg, L.J. T cell receptor - initiated calcium release is uncoupled from capacitative calcium entry in Itk - deficient T cells.

More recent evidence shows that an alternative second messenger, nicotinic acid adenine dinucleotide phosphate (NAADP), also has a role to play, causing researchers to question established calcium releasing pathways.

Many intracellular sensors of events like calcium release have been made using fluorescent resonance energy transfer (FRET) probes.

cardiomyocytes exhibit decreased peak shortening and maximal velocity of shortening / relengthening, prolonged time - to - 90 % relengthening, reduced intracellular calcium release upon electrical stimulus associated with a slowed intracellular calcium decay rate, and significantly higher oxygen levelse, and significantly higher oxygen levels

Higher doses increase the force of muscle contractions, possibly by stimulating more calcium release from the sarcoplasmic reticulum of muscle cells.

Inhibition of both oxytocin - induced contraction and calcium release by the traditional NAADP - signaling disrupter bafilomycin and the NAADP receptor antagonist Ned - 19 clearly demonstrated a role for NAADP in oxytocin - induced signaling.

In particular, several groups have observed defective intracellular calcium release from the sarcoplasmic reticulum in fatigued skeletal muscle, although no mechanisms have been established.

Responses were correlated to calcium release in cultured rat uterine smooth muscle cells measured by fluorescence microscopy.

Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion.

This might be because adaptor molecules like RhoH and SLP76 can affect the signaling events downstream of calcium release from the ER, or might indicate the existence for a possible positive feedback pathway from calcium signaling to the upstream of adaptor molecules.

CM4620 is a potent and selective small molecule inhibitor of calcium release - activated calcium (CRAC) channels.

Rome and colleagues therefore measured the amount of calcium released and pumped by midshipman swimbladder muscles as they repeatedly contract and relax.

A cell - permeant form of NAADP was able to produce both uterine contractions and calcium release.