Sentences with word «endoplasmic»

Bottom: Human epithelial cells from breast tissue showing the effects of endoplasmic reticulum stress (blue) which fills the entire cell structure.

Hypertension drug that protects cell from endoplasmic reticulum stress and preserves oligodendrocytes and myelin during inflammation

Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum - 2006 International Journal of Molecular Medicine.

SV = Secretory vesicle; RER = Rough endoplasmic reticulum; BM = Basement membrane; MFG = Milk fat globule; CLD = Cytoplasmic lipid droplet; N = Nucleus; PC = Plasma cell; FDA = Fat - depleted adipocyte; TJ = Tight junction; GJ = Gap junction; D = Desmosome; ME = Myoepithelial cell.

Understand the membrane dynamics of autophagasome biogenesis and its putative crosstalk with endoplasmic reticulum contact sites

Disruptions in a protein folding process occurring in the brain, known as endoplasmic reticulum (ER) stress, may cause non-alcoholic fatty liver disease, independent of other factors.

Link between Endoplasmic Reticulum Turnover and Neurodegeneration in Alzheimer's 1 Jin Rui Liang, PhD University of California, Berkeley (Berkeley, CA)

A cell biologist at the University of Colorado Boulder, Voeltz was studying a humble part of the cell called the ER, for endoplasmic reticulum.

Because most if not all people with MS experience nerve cell damage, researchers have begun to focus on two organelles within the neuron's cell body: the power - generating mitochondria and the labyrinth - like endoplasmic reticulum, which makes many of the proteins, lipids and other molecules needed by the cell.

It turns out that neuropathic pain is triggered when the body experiences endoplasmic reticulum (ER) stress, a condition in which the production and transport of protein exceeds the cells» capacities, say researchers from the University of California, Davis.

The Hu laboratory studies endoplasmic reticulum (ER), which has critical functions in lipid synthesis, calcium storage and drug metabolism.

The unfolded protein response is partially activated in PEL, but is fully activated in plasma cell tumors, linking endoplasmic reticulum stress to plasma cell development through XBP - 1.

Eukaryotic - specific signal recognition particle and receptor components stabilize the ribosomal endoplasmic reticulum — targeting complex.

In this research, the scientists disturbed endoplasmic reticulum function by introducing saturated fatty acids into cells to induce lipotoxic stress.

Though the UPR usually promotes healthy endoplasmic reticulum function, sustained UPR activation sometimes results in diseases such as atherosclerosis, the deposition of fatty plaques on artery walls, among other conditions.

Domains that contained dilysine endoplasmic reticulum retrieval signals bound the α -, β ′ -, and ϵ - COP subunits of coatomer, whereas other p24 domains bound the β -, γ -, and ζ - COP subunits and required a phenylalanine - containing motif.

In addition, gastrocnemius muscles from IL - 15Rα — KO mice expressed higher levels of mRNA for the sarcoplasmic endoplasmic reticulum calcium ATPase - II (SERCA2) and lower mRNA expression and protein content of the calcium - binding protein calsequestrin (Figure 5, F and G).

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress — Related Genes

But, what if an FP fusion with a resident endoplasmic reticulum (ER) protein instead localizes to the cytoplasm?

He investigates endoplasmic reticulum - associated stress signaling molecules, which play important roles in the quality control of secretory and integral membrane proteins.

Alcohol consumption generates oxidative stress and inflammation and the potential to disrupt endoplasmic reticulum homeostasis; a consequence of this response is to limit the rate of protein synthesis [44], [45].

The self - test asks, «Write a sentence that uses the words endoplasmic reticulum correctly.»

The corrected paper is a review in the Journal of Virology — known there as a Gem — which discusses how viruses use the membranes of endoplasmic reticulum (ER) to replicate.

Using a embroidery thread make french knots along the outer edge of the rough endoplasmic reticulum.

The evolving role of ubiquitin modification in endoplasmic reticulum - associated degradation

Protein trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus involves specific uptake into coat protein complex II (COPII)-- coated vesicles of secretory and of vesicle targeting (v - SNARE) proteins.

They also saw differences in the shape of the cells» mitochondria and endoplasmic reticulum structure among other differences.

Regulation of Protein Secretion Through Controlled Aggregation in the Endoplasmic Reticulum

When it reaches the brain, Zika virus infects neuronal stem cells, which will generate fewer neurons, and by inducing chronic stress in the endoplasmic reticulum, it promotes apoptosis, i.e. the early death of these neuronal cells.

A protein was engineered so that it accumulated as aggregates in the endoplasmic reticulum.

They showed that ZIKV infection of cortical progenitors (stem cells for cortical neurons) controlling neurogenesis triggers a stress in the endoplasmic reticulum (where some of the cellular proteins and lipids are synthetized) in the embryonic brain, inducing signals in response to incorrect protein con - formation (referred to as «unfolded protein response»).

In the online issue of the journal Nature, the researchers report a new function of FAM134B in the constant renewal of the endoplasmic reticulum (ER), an important cell organelle.

It gloms on to the surfaces of the endoplasmic reticulum and mitochondria, controlling the organelles» interactions and mitochondrial behavior.

Endoplasmic reticulum stress is triggered not only by protein - folding problems, but also by fatty acids, explained Acosta - Alvear.

When improvising in the lab, she investigates vesicle formation at the endoplasmic reticulum.

Oligodendrocytes have mitochondria and an endoplasmic reticulum too.