Sentences with word «entorhinal»

Finally, Morgan Barense will report that the impoverished representations of visual objects that are characteristic of Alzheimer's disease are associated with abnormal viewing patterns related to volumetric reductions in entorhinal cortex.

Microstimulation in the right entorhinal area during learning significantly improved subsequent memory specificity for novel portraits; participants were able both to recognize previously - viewed photos and reject similar lures.

To determine how information is represented in this area, we measured spatial modulation of neural activity in layers of medial entorhinal cortex projecting to the hippocampus.

They investigated how nerve signals are suppressed inside the so - called entorhinal cortex.

Several types of hippocampal and entorhinal neurons are capable of generating theta - frequency membrane potential oscillations when stimulated.

«Alzheimer's starts at least 30 years before it's diagnosed,» says Banner Health neurobiologist Paul Coleman, who works with entorhinal cortex from the brain bank himself.

In fact, in this figure, we erroneously included the MRI image from the RIGHT entorhinal cortex, rather than the left.

Theta - burst microstimulation in the human entorhinal area improves memory specificity.

To determine whether direct entorhinal connections support spatial firing and spatial memory, we removed all input from areas CA3 to CA1, thus isolating the CA1 area.

«By observing entorhinal - hippocampal neurons based on their birthdate, we realized that these cells were somehow special and very different from the other surrounding cell types, which was instrumental to find out how and to what extent they influenced the assembly of the network.»

While aerobic fitness is not directly associated with performance on a recognition memory task, the participants with a larger entorhinal cortex also performed better on the recognition memory task.

In contrast, the researchers did not find age - related differences in another area of the brain connected to memory, the posteromedial entorhinal cortex.

They found that it was linked to a loss of signaling in a part of the brain called the anterolateral entorhinal cortex.

The gradual refinement of the spatial representation is accompanied by an increase in network synchrony among entorhinal stellate cells.

Level of sustained entorhinal activity at study correlates with subsequent cued - recall performance: a functional magnetic resonance imaging study with high acquisition rate.

To optically manipulate specific connections to these engram cells, a blue light - sensitive protein oChIEF was expressed in an upstream brain region, i.e., medial entorhinal cortical inputs (red) to the DG.

OBJECTIVE To use fMRI to investigate whether hippocampal and entorhinal activation during learning is altered in the earliest phase of mild cognitive impairment (MCI).

Hyperexcitability in combined entorhinal / hippocampal slices of adult rat after exposure to brain - derived neurotrophic factor

We now need to investigate the effect in more complex navigational tasks, but I would expect the differences in entorhinal activity to have a larger impact on more complex tasks.

Thank you for submitting your article «Theta - burst microstimulation in the human entorhinal area improves memory specificity» for consideration by eLife.

Border cells are relatively sparse, making up less than 10 % of the local cell population, but can be found in all layers of the medial entorhinal cortex as well as the adjacent parasubiculum, often intermingled with head - direction cells and grid cells.

These results suggest that the hippocampus contains two functionally separable memory circuits: The direct entorhinal - CA1 system is sufficient for recollection - based recognition memory, but recall depends on intact CA3 - CA1 connectivity.

We have corrected this error and note that in the LEFT entorhinal cortex, the microelectrode is indeed in the white matter, so no statistics or analyses from the manuscript text were affected.

We show that theta - burst microstimulation of the right entorhinal area, applied prior to stimulus onset, enhanced memory specificity for these photographs.

A rat's position in space can be represented in the medial entorhinal cortex in addition to the neighboring hippocampus, the area previously thought to be the only locus of spatial information.

«We have now been able to show that the rate at which the speedometer cells fire influences neuronal activity in the entorhinal cortex.

When the firing rate increases, activity in the entorhinal cortex increases too.

This includes an area called the «entorhinal cortex» which is considered to be the brain's navigation center.

Humans have similar neural pathways connecting the medial septum and entorhinal cortex.

Some people's electrodes were in the entorhinal cortex's gray matter, and some were in its white matter fibers, which extend to the hippocampus, an area known for its role in memory.

Memory enhancement and deep - brain stimulation of the entorhinal area.

Advancements in intracranial stimulation of the entorhinal area for enhancement of episodic memory.

A groundbreaking study by Suthana and colleagues, published in 2012 the New England Journal of Medicine, found that people performed better on a memory task if their entorhinal cortex — a brain hub for memory and navigation — was given a low jolt of electricity during the task.

Follow - up work by Suthana suggests that activating the entorhinal cortex isn't enough: Targeting a particular path of nerve fibers matters.

As the interface between hippocampus and neocortex, the entorhinal cortex is likely to play a pivotal role in memory.

Precise positional modulation was not observed more ventromedially in the entorhinal cortex or upstream in the postrhinal cortex, suggesting that sensory input is transformed into durable allocentric spatial representations internally in the dorsocaudal medial entorhinal cortex.

Rats have cells in their brains» entorhinal cortex that appear to generate an internal grid of triangles, and which fire as the animals navigate around a space.

Close to the postrhinal - entorhinal border, entorhinal neurons had stable and discrete multipeaked place fields, predicting the rat's location as accurately as place cells in the hippocampus.

When Donato's team silenced the neurons, the part of the brain known to function in memory and navigation, called the entorhinal - hippocampal region, did not develop properly.

The surgeon, William Scoville, had removed the front sections of both of Henry's hippocampi, along with much of his entorhinal, perirhinal, and hippocampal cortices, now understood to be crucial to memory.

To remedy this, Donato pioneered a strategy that allowed his team to find the neurons responsible for building the entorhinal - hippocampal region targeted toward the developing brains of mice at specific time points.