Sentences with phrase «epigenetic control»
Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.
mdanderson.org
One such surprise was the relative importance of two types of epigenetic control switches for retinal development.
There are several pieces of evidence showing that loss of epigenetic control over complex immune processes contributes to autoimmune disease.
Stress, epigenetic control of gene expression and memory formation.
Sung Hee Baek talked about chromatin modifiers in epigenetic control of cancer and stem cells.
David Baker said that «for more than 20 years my lab has been interested in identifying a malaria parasite gene underlying the switch to sexual development and finally the ap2 - g locus, under epigenetic control, has come to light.»
«Instead, those people might have mutations in epigenetic controls called «enhancers.»
«The stability of the global lipidome with age, diet and over time is unknown, and the influence of external factors such as epigenetic control of lipid metabolizing enzymes could be considerable.»
Step one of the environmental epigenetic control pathway is that the cell initiates a specific change to one amino acid in a protein named JMJD1A and this altered JMJD1A recruits other proteins.
This is number two in my series of blogs on epigenetic control of genome restructuring and hereditary transmission of traits...
That means epigenetic control of SOD activity through a vegetarian diet confers the very damage protection we need to realize advanced age in good health.
We can not use randomized controlled experiments with people but do so with animals, demonstrating, for example in Michael Meaney's lab, that affectionate touch in early life is critical for epigenetic controls of anxiety in mammals.
In addition, they demonstrate that the repression mechanism of Chrono is under epigenetic control and links, via a glucocorticoid receptor, to metabolic pathways triggered by behavioral stress.
This information can help parents understand that babies need responsiveness and lots of touch and movement to develop self - regulation (e.g., vagus nerve; Porges, 2011), epigenetic controls of anxiety, and the stress response (HPA axis; McEwan, 2003) from the first moments after birth.
He plans to do genomewide analysis to identify new genes with a role in the epigenetic control of LINE - 1 mobility, and to go looking for more cell types where LINE - 1 mobility occurs.
Unravelling the epigenetic control of the lactase gene involved a collaborative effort of CAMH, University of Toronto, the Hospital for Sick Children, Vilnius University and the Lithuanian University of Health Sciences.
«A large number of quiescent hematopoietic stem cells was activated simultaneously when the epigenetic control provided by genomic imprinting was removed,» explains Venkatraman.
The specific pattern of epigenetic marks in a cell type specifies identity and this epigenetic control is vital to what makes our cells different, for example a skin cell from a liver cell, when they all contain the same genetic instructions.
Consequently, the Zurich - based researchers studied whether epigenetic factors are especially active in melanoma cells — and stumbled across EZH2, an epigenetic control protein found very frequently in malignant melanoma cells compared to normal cells.
Epigenetic controls are molecular switches that turn genes on or off to orchestrate a cell's development from a generic cell to a specialized cell like a neuron.
«Our own understanding of the genetic and epigenetic control of ripening and the metabolic pathways that contribute to nutrient quality has been improved,» said Giovannoni.
A major aspect of our work centers around transcriptional and epigenetic control of plasticity in cardiomyocytes, smooth muscle, and skeletal muscle in physiology and disease.
We attempt to understand how the organisation of chromatin determines the epigenetic control of T cell responses in vitro and in vivo.
As a partner of the European Consortium 3D - REPERTOIRE and coordinator of the Spanish Structural Genomics Consortium GENES, our group studies several protein complexes and molecular machines, some of which are related to the epigenetic control of gene expression.
If we continue to advance in the study of endocannabinoids, another report entitled «Epigenetic control of skin differentiation genes with phytocannabinoids» confirms that the endocannabinoid system plays a role in epidermal physiology.
Next up was Didier Trono who talked about how transposable elements and their epigenetic control mechanisms are key regulators of transcriptional networks in PSCs.
«In addition to genetic and epigenetic control of BDNF, prebiotics and diet regulate BDNF levels, which suggests a potential microbial - directed mechanism.»
The study of epigenetic control is revolutionizing how the medical community thinks about genes.