Sentences with phrase «for transcription factors»

All of these genes code for transcription factors, which are proteins that control the expression of other genes.
The parcel of genetic information that is required for the transcription factor's synthesis, known as messenger RNA, shows specific structural differences.
However, if the genes for the transcription factors Olig3 or Tlx3 are mutated, the nerve cells in this particular nucleus can not mature properly in the fetus.
What's important about the discovery is that MER41's bits and pieces include binding sites for transcription factors involved in fighting infections.
This study reports on an important role for transcription factor FoxM1 in the maintenance of SCs.
«The problem is that there is so much DNA in a cell that it would be impossible for the transcription factors to find their way back within a reasonable time frame.
Amjad Javed, Ph.D., and University of Alabama at Birmingham colleagues have found a key role in tooth development for the transcription factor Specificity protein 7, or Sp7.
Requirement for the transcription factor LSIRF / IRF4 for mature B and T lymphocyte function.
In the second webinar, you will learn how to apply basic concepts of flow cytometry to topics such as cell proliferation, dead cell exclusion, and intracellular staining techniques for transcription factors and phospho - proteins.
Besides, some other potential cis - acting elements for transcription factors [such as CAAT / enhancer binding protein (C / EBP) and PU.1] have been also noted in the RIG - G gene promoter.
Previous studies have hinted at a possible role for the transcription factor Peroxisome Proliferator - Activated Receptor alpha (PPARα) in cold - induced browning.
As the target sequences for transcription factors are short, and transcription factors are tolerant of considerable variation in the sequences to which they bind, it is extremely difficult to distinguish functional binding sites in the vastness of the human genome.
When the chimp and human genomes are compared, some of the clearest cases of nucleotide differences are found in genes coding for transcription factors.
By studying Arabidopsis plants for which the genes for these transcription factors had been selectively knocked out, the group identified a single transcription factor that when inactive resulted in longer roots.
Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown gene that appears to code for a transcription factor — a protein that switches other genes on or off.
These observations indicate that the gene for a transcription factor is located at the breakpoint of a consistently recurring chromosomal translocation in many acute leukemias and suggest a direct role for alteration of such factors in the pathogenesis of some malignancies.
Interestingly, not only the DNA that codes for these transcription factor genes is shared among the deuterostomes, but also some of the DNA pieces that are used as binding sites for the transcription factors are conserved among these animals.
The genes for each transcription factor were made from different bits of DNA that code for the functional parts of proteins, such as a domain that can bind to DNA and another that provides the protein with access to the cell's nucleus.
Using novel gene - array technology to measure the extent of gene expression in thousands of genes simultaneously, this study shows that as humans diverged from their ape ancestors in the last five million years, genes for transcription factors — which control the expression of other genes — were four times as likely to have changed their own expression patterns as the genes they regulate.
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