Thus, we provide a robust technology and the first comprehensive resource to address fundamental questions regarding
maintenance of cell identity,» says associate professor Anja Groth, who is heading the laboratory.
This classic work has inspired several generations of scientists to discover
mechanisms of cell identity, which have informed a lot of the discoveries in stem cell biology and reprogramming that have followed.
The
understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.