Sentences with phrase «of gene expression»

The scientists then studied the patterns of gene expression in these mice.

The same can be said for patterns of gene expression changes in the same brain region for different age frames.

They develop new techniques to quantify gene expression and study the regulation of gene expression in single cells.

Evaluation of the levels of gene expression in these blood samples showed a distinct change in RA patients who had responded to treatment.

Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.

A study of gene expression in leukemia cells has identified an RNA binding protein that plays an important role in driving the development of cancer.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

The main research focus of the single molecule group is the study of molecular motors, the role of force in regulating biological systems, and the molecular mechanisms of gene expression regulation.

An analysis of gene expression of the known fungal partner in the two species showed no differences.

More recent research on the epigenetic modification of gene expression by early maternal care in animals suggests the possibility of similar processes affecting human development.

The research revealed fascinating physical similarities, and differences, in the patterns of gene expression across disorders including autism and schizophrenia.

The transmission of different states of gene expression through multiple cell divisions and across generations has been termed «epigenetic,» since the underlying DNA sequence is identical in both states.

It is situated just next to a thyroid - specific transcription factor, a protein that regulates the rate of gene expression in the thyroid.

It is an important factor for the correct regulation of gene expression within all these groups of organisms.

These epigenetic modifications do not change the genetic code, but may contribute to the inhibition of gene expression, causing the cells to produce smaller amounts of the corresponding proteins.

We also study how changes in the timing of gene expression contribute to diseases like cancer.

First, an adult cell would be removed from a patient and the DNA of that cell altered to control and direct the types of gene expression the nucleus is capable of supporting.

Our fundamental knowledge of gene expression is being applied systematically to more precise diagnosis of disease and its subsequent treatment.

However, to make use of that information required an understanding of gene expression and regulation, areas in which institute members made a conscious decision to invest and that became its strengths.

When inherited from both parents, the lack of gene expression can cause mild to severe intellectual disability, autism, and / or seizures.

How does regulation of gene expression determine inner ear function on a genetic and epigenetic level?

When these mice develop, their internal organs and patterns of gene expression fall randomly into left - or right - oriented layouts.

A new computational method can improve the accuracy of gene expression analyses, which are increasingly used to diagnose and monitor cancers and are a major tool for basic biological research.

But brain cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were created from young donors or older adults.

Luckily, a mouse model already existed that allowed the team to take advantage of this gene expression and use it to compare the two cell populations.

Different levels of gene expression give each cell its specific characteristics and function through the production of different proteins.

And, how few mutations can give rise to new features of gene expression?

We show, for the first time, the influence of the gene expression levels demonstrating the power of «big data» to change how medical research is performed.

Early in vitro analyses of gene expression revealed that the cell lines were germ - cells, our target cell type.

This can then be used to create computational estimates of gene expression levels from any whole genome sequence or chip dataset.

Recent research in applied single - molecule experimentation of living cells has begun real - time imaging of gene expression, at both transcription and translation levels.

The discovery of gene expression has changed all that.

Acting like a volume knob for genes, these tags adjust the intensity of gene expression.

Stress, epigenetic control of gene expression and memory formation.

To understand and analyze the regulation of gene expression patterns, quantitative RNA sequencing is used.

But when the researchers placed the embryos in fluid flowing to the left, they developed normal patterns of gene expression and heart development.

The tool then uses information from similar cells to make an educated guess about what the level of gene expression should be.

Unfortunately, direct comparisons of gene expression profiles obtained in independent, publicly available microarray experiments are typically compromised by substantial, experiment - specific biases.

Comparison of gene expression profiles showed a low number of differentially expressed transcripts among the three ES cell lines.

Karolina Jastrezbowska (Tomancak, MPG)-- «Evolution of gene expression regulation during embryonic development of Drosophila species» (2010)

And next - generation sequencing, in particular, RNA sequencing, allows researchers to delineate changing patterns of gene expression as new cell types form.

These eSTRs explain on average 10 to 15 % the genetic differences of gene expression between individuals.