Sentences with phrase «of tumour cells»

He said, «it is not just the local growth of tumour cells that makes them so lethal, it is their ability to spread directly through invasion and by metastases to other side of the body.

Ovarian cancer researchers have identified a protein biomarker expressed on the surface of tumour cells in high - grade serous ovarian cancer, the most common and lethal subtype of the disease.

They found that the resulting death of the tumour cells led to an inflammatory response in which white blood cells converged on the tumour and secreted a signalling molecule called lymphotoxin.

Being a signal protein in the cell membrane of tumour cells, HER2 stimulates malign growth and survival.

Now a team led by Anne - Maree Pearse of Tasmania's department of primary industries has performed a genetic analysis of tumour cells from 37 animals.

Research fields are diverse, including basic research on cell proliferation, analysis of tumour cells and tissues to detect gene mutations, and identification of potential therapeutic targets in cancer.

The team plans to test the approach in a clinical trial in which chemotherapy drug selection for each person will be guided by testing balls of their tumour cells in the lab.

Adrian Harris of the Institute of Molecular Medicine (IMM) in Oxford and his colleagues have developed a genetic «switch» that will start the production of a lethal protein in the 10 per cent of tumour cells that are ultra-resistant.

Under the supervision of Claudia Binder, MD / PhD, I also carry out research, examining the interactions of tumour cells and macrophages.

Last December, a sample of tumour cells from the patient's lung was sent to Somatix Therapy, a biotechnology company in Alameda, California.

This mechanism increases the volume of tumour cells exposed to reactive species.

Therefore, «this finding may represent a future therapeutic strategic to combine with other strategies, such as immunotherapy, chemotherapy or inhibitors against specific signalling routes of the tumour cells.»

Also characteristics of tumour cells such as a protein which is too abundant in the cell envelope are called antigens.

The decrease in metastasis caused by melanoma cells was especially dramatic and confirmed that NK cells lacking STAT3 are extremely efficient killers of tumour cells.

In future, other switches could be identified in other types of tumour cell.

These proteins play an important role in the drug resistance of tumour cells and bacteria.

In the genome of tumour cells of 11 patients, the scientists observed the insertion of a viral DNA segment from adeno - associated virus type 2, known as AAV2.

Throughout my research career as a translational clinician - scientist I have had an abiding interest in the mechanisms of tumour cell growth, and the development of innovative strategies to improve diagnosis and therapy for cancer patients.

Although all neoplastic cells arose from Prom1 (+) cells in these mice, only 7 % of tumour cells retained Prom1 expression.

Development of nanotechnology for targeting in vivo inflammatory processes of tumour cells for diagnostic or therapeutic purposes.

Cellular senescence, which halts the proliferation of damaged or dysfunctional cells, is an important mechanism to constrain the malignant progression of tumour cells.

This review explores the mechanistic basis of tumour cell invasion by focusing on the reorganisation of the dendritic actin network.

The first step is to understand how a small fraction of the tumour cells often escape therapy while becoming more malignant.

When a protein is more abundant on the cell surface of tumour cells, the immune system has already been sensitised and will react.»

This would then use the protein to recognise a foreign or tumour cell, attach to it and release the toxin in a high local concentration, which would cause the death of the tumour cell.

One of the most used and most effective strategies in cancer treatment are drugs targeting microtubules, which halt the growth of tumour cells and induce apoptosis or programmed cellular death.

KEYNOTE - 024 investigated the efficacy of pembrolizumab compared to standard of care with platinum - based chemotherapy in untreated patients with advanced NSCLC and high PD - L1 expression (defined as expression in at least 50 % of tumour cells).

The researchers then used a specific tool to block the CD15s on the surface of the tumour cells, and this prevented the NSCLC cells from attaching to the blood vessels.