Sentences with phrase «peptide sequences»

An animal study looked at the short - term oral atihypertensive effect of peptide sequences isolated from casein fractions that had been previously documented as in vitro angiotensin - converting enzyme inhibitors.

Briefly, trastuzumab heavy and light chain sequences were amplified with PCR and a truncated FMDV 2A peptide sequence was inserted between them by splice overlap extension.

«We employed a custom bioprospecting approach combining partial de novo peptide sequencing with transcriptome assembly to identify cationic antimicrobial peptides from Komodo dragon plasma,» the authors explained.

Although the reasons why Plasmodium proteins are difficult to express in heterologous expression systems are not clear, several protein characteristics, such as high molecular mass (> 60 kDa), presence of export motifs, and atypical signal peptide sequences negatively impact recombinant expression [12].

Researchers at Stanford University purified the proteasome from the malaria parasite and examined its activity against hundreds of different peptide sequences using a novel method developed at the University of California, San Francisco.

The XLPRA2 mutation is a 2 nucleotide deletion that results in a frameshift that significantly changes the predicted peptide sequence by leading to the replacement of many acidic glutamic acid residues with basic arginine residues and results in the premature termination of the protein 71 amino acids downstream.

In order to find the best protein or peptide sequence for a specific function, they must simulate thousands of designs and search for the most effective option.

«What's critical with this and what has never been done before is that a single peptide sequence will work against the toxic versions of a number of different amyloid proteins and peptides, regardless of their amino acid sequence or the normal 3 - D structures.»

Since antibacterial peptides specifically target and disrupt the integrity and function of bacterial membranes, we thought that these similar peptide sequences in the HIV envelope protein might contribute to toxicity and death in infected cells by altering cell membranes.»

The scientists found similarities in HLA - bound peptide sequences between human and hCMV genomes.

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries — Steven Shave — PLOSone

Frozen sections of lung and colon tissues from wild - type mice and Slc6a14 − / − mice were also used for immunofluorescence analysis of Slc6a14 protein expression with an antibody raised against a mouse peptide sequence [17].

RANbodies are expressed in 293T cells and are secreted from cells due to their IgGκ signal peptide sequence, making them easy to harvest from cell culture media.

Sun decided to study a fraction of the peptide sequence that gave the glue its adhesive ability by attaching a heterogeneous hydrophilic peptide segment inspired by spider silk proteins.

When a specific SAP is found in the peptide sequence, the investigator knows that individual had the DNA to produce that polymorphism.

If the polymorphisms in all the peptide sequences are consistent with those of a suspect, then that suspect can be associated with the evidence.

Peptides are complex molecules and each peptide sequence is unique with regard to its chemical and physical properties.

Typically, companies in the pharmaceutical and biotechnology industries file patents protecting small molecules, biologics (an antibody, peptide sequence, etc), methods of treatment or unique (diagnostic) assays (for detecting and / or treating disease).